Lysimachia christinae
Lysimachia christinae
Lysimachia christinae, a plant native to East Asia, has not been traditionally used for medicinal purposes. Scientific research indicates that extracts from this plant may reduce kidney stone formation in rats by modulating the NOX2/ROS axis and ferroptosis, and also show superior antioxidant activity and kidney stone inhibitory effects compared to those extracted by hot water. Additionally, Lysimachia christinae aqueous extract has been shown to improve renal injury and oxidative stress in both kidney stone rats and HK-2 cells by activating the Nrf2/HO-1 pathway and inhibiting PI3K/Akt/mTOR. The distribution of this plant is predicted to vary significantly under different Shared Socioeconomic Pathways, with habitat stability dependent on thermal variables. To date, no major safety issues or drug interactions have been recorded for Lysimachia christinae.
- أفضل دليل
- D
- تحذيرات
- —
للمعلومات فقط. الاستخدام التقليدي لا يعني فعاليّة مثبتة. تختلف الأدلة والسلامة — راجع المصادر المذكورة.
ما يقوله العلم
- استخلص ليسيماتشيا CHRISTINA خفض تكوين الحصوات الكلوية في الفئران عن طريق تنظيم مسار NOX2/ROS وفيرروبيتوسية.
- البولي ساكاريدات ليسيماثيا christinae Hance التي تم استخراجها باستخدام التقطيع الموجه بالتردد العالي أظهرت نشاط مضاد للأكسدة وتأثير منع حصى الكلى أفضل مقارنة بالاستخراج بالماء الساخن.
- الاستخراج المائي من Lysimachia christinae يحسن الضرر الكلوي والضغط الأكسدي في الفئران المصابة بالحصوات الكلوية وخلايا HK-2 عن طريق تنشيط Nrf2/HO-1 وإيقاف PI3K/Akt/mTOR.
- وجدت الدراسة أن توزيع Lysimachia christinae يتأثر بالمتغيرات الحرارية، مع أن استقرار الموطن يتغير تحت مختلف سيناريوهات المناخ.
Frequently asked questions
What is Lysimachia christinae?
Lysimachia christinae (Lysimachia christinae) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Lysimachia christinae?
4 sourced findings are recorded for Lysimachia christinae; the strongest carries evidence grade D. For example: استخلص ليسيماتشيا CHRISTINA خفض تكوين الحصوات الكلوية في الفئران عن طريق تنظيم مسار NOX2/ROS وفيرروبيتوسية.
How strong is the evidence for Lysimachia christinae?
The strongest finding for Lysimachia christinae carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Lysimachia christinae safe? What are the side effects?
No major safety issues are recorded for Lysimachia christinae in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Lysimachia christinae interact with medications?
No drug interactions are recorded for Lysimachia christinae in our sources. This does not rule them out — check with a pharmacist.
Is Lysimachia christinae a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
المصادر
- T2 Assessing Climate Change Impacts on Distribution Dynamics of Lysimachia Christinae in China Through MaxEnt Modeling. literature abstract metadata
- T2 Lysimachia christinae Hance aqueous extract ameliorates renal injury in kidney stone rats and calcium oxalate crystal-induced oxidative stress in HK-2 cells via inhibiting the PI3K/Akt/mTOR pathway. literature abstract metadata
- T2 Application potential of Lysimachia christinae Hance polysaccharides in kidney stone prevention/treatment: a multidimensional comparison between ultrasonic-assisted extraction and hot water extraction. literature abstract metadata
- T2 Lysimachia christinae Hance Extract Mitigates Kidney Stone Formation: Association with NOX2/ROS Axis Modulation and Ferroptosis. literature abstract metadata