Lysimachia christinae
Lysimachia christinae
Lysimachia christinae, a plant native to East Asia, has not been traditionally used for medicinal purposes. Scientific research indicates that extracts from this plant may reduce kidney stone formation in rats by modulating the NOX2/ROS axis and ferroptosis, and also show superior antioxidant activity and kidney stone inhibitory effects compared to those extracted by hot water. Additionally, Lysimachia christinae aqueous extract has been shown to improve renal injury and oxidative stress in both kidney stone rats and HK-2 cells by activating the Nrf2/HO-1 pathway and inhibiting PI3K/Akt/mTOR. The distribution of this plant is predicted to vary significantly under different Shared Socioeconomic Pathways, with habitat stability dependent on thermal variables. To date, no major safety issues or drug interactions have been recorded for Lysimachia christinae.
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- Lysimachia christinae 提取物通过调节 NOX2/ROS 轴和铁死亡途径减少了大鼠肾结石的形成。
- Lysimachia christinae Hance多糖通过超声辅助提取显示出比热水提取的抗氧化活性和肾结石抑制作用更强的效果。
- Lysimachia christinae 水提取物通过激活 Nrf2/HO-1 并抑制 PI3K/Akt/mTOR 来改善肾结石大鼠和 HK-2 细胞中的肾脏损伤和氧化应激。
- 研究发现，lysimachia christinae 的分布受温度变量的影响，在不同气候情景下栖息地稳定性会有所不同。
Frequently asked questions
What is Lysimachia christinae?
Lysimachia christinae (Lysimachia christinae) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Lysimachia christinae?
4 sourced findings are recorded for Lysimachia christinae; the strongest carries evidence grade D. For example: Lysimachia christinae 提取物通过调节 NOX2/ROS 轴和铁死亡途径减少了大鼠肾结石的形成。
How strong is the evidence for Lysimachia christinae?
The strongest finding for Lysimachia christinae carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Lysimachia christinae safe? What are the side effects?
No major safety issues are recorded for Lysimachia christinae in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Lysimachia christinae interact with medications?
No drug interactions are recorded for Lysimachia christinae in our sources. This does not rule them out — check with a pharmacist.
Is Lysimachia christinae a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Assessing Climate Change Impacts on Distribution Dynamics of Lysimachia Christinae in China Through MaxEnt Modeling. literature abstract metadata
- T2 Lysimachia christinae Hance aqueous extract ameliorates renal injury in kidney stone rats and calcium oxalate crystal-induced oxidative stress in HK-2 cells via inhibiting the PI3K/Akt/mTOR pathway. literature abstract metadata
- T2 Application potential of Lysimachia christinae Hance polysaccharides in kidney stone prevention/treatment: a multidimensional comparison between ultrasonic-assisted extraction and hot water extraction. literature abstract metadata
- T2 Lysimachia christinae Hance Extract Mitigates Kidney Stone Formation: Association with NOX2/ROS Axis Modulation and Ferroptosis. literature abstract metadata