Checkerberry
Gaultheria procumbens
Gaultheria procumbens, commonly known as wintergreen, is a traditional plant used primarily in North American indigenous medicine. While its specific uses are not well-documented, it has been traditionally employed for various ailments. Scientific evidence suggests that essential oils from Gaultheria procumbens exhibit antifungal properties against certain fungal isolates. Additionally, studies indicate that extracts of the plant can alleviate oxidative stress and modulate inflammatory responses in cell-based models, with some formulations showing more significant effects than others. However, due to limited research, these findings should be interpreted cautiously. No major safety concerns or drug interactions have been reported for Gaultheria procumbens, though further investigation is warranted to fully understand its potential benefits and risks.
- Beste Evidenz
- D
- Warnhinweise
- —
Nur zur Information. Traditionelle Anwendung bedeutet keine nachgewiesene Wirksamkeit. Evidenz und Sicherheit variieren — siehe die angegebenen Quellen.
Was die Wissenschaft sagt
- Die Studie zeigte an, dass Öle aus Gaultheria procumbens, zusammen mit anderen, eine antifungale Wirkung gegenüber bestimmten Pilzisolaten aufweisen.
- Beide Formulierungen AS632 und AS633 zeigten signifikante entzündungshemmende und antioxidative Wirkungen, wobei AS632 stärker TNF-α-Suppression in Makrophagen demonstrierte.
- (6S,9R)-Vomifoliol aus Gaultheria procumbens zeigte anti-entzündliche und antioxidative Effekte an menschlichen Immunzellen in vitro.
- NJH verringerte das antioxidative Stress-Syndrom in den NRK-52E-Zellen durch Aktivierung der AMPK/Nrf2/HO-1-Signalkette und Modulation von Apoptose-verwandten Proteinen.
Frequently asked questions
What is Checkerberry?
Checkerberry (Gaultheria procumbens) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Checkerberry?
4 sourced findings are recorded for Checkerberry; the strongest carries evidence grade D. For example: Die Studie zeigte an, dass Öle aus Gaultheria procumbens, zusammen mit anderen, eine antifungale Wirkung gegenüber bestimmten Pilzisolaten aufweisen.
How strong is the evidence for Checkerberry?
The strongest finding for Checkerberry carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Checkerberry safe? What are the side effects?
No major safety issues are recorded for Checkerberry in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Checkerberry interact with medications?
No drug interactions are recorded for Checkerberry in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Checkerberry?
Checkerberry is also known as: Гаультерия лежачая, Gaulthérie couchée.
Is Checkerberry a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Quellen
- T2 Anti-Inflammatory and Antioxidant Effects of (6S,9R)-Vomifoliol from Gaultheria procumbens L.: In Vitro and Ex Vivo Study in Human Immune Cell Models. literature abstract metadata
- T2 Exploring the potential of essential oils against airborne fungi from cultural heritage conservation premises. literature abstract metadata
- T2 Ameliorative Effects of the Neng-Jing-Huo Essential Oil Blend on H2O2-induced Oxidative Stress Injury in NRK-52E Cells via the AMPK/Nrf2/HO-1 Signaling Pathway. literature abstract metadata
- T2 Anti-Inflammatory and Antioxidant Effects of Topical Formulations Containing Plant Extracts, Methylsulfonylmethane, and Peptiskin® in In Vitro Models of Arthritis. literature abstract metadata