Checkerberry
Gaultheria procumbens
Gaultheria procumbens，又称冬青，是一种传统植物，在美洲原住民医学中被使用。虽然其具体用途在历史传统中没有详细说明，但这种植物已被研究以探索各种潜在的健康益处。科学证据表明，该植物的精油具有抗真菌活性，并显示出显著的抗炎和抗氧化作用，特别是AS632配方在巨噬细胞中对TNF-α的抑制作用更强。Gaultheria procumbens中的(6S,9R)-vomifoliol异构体也在人类免疫细胞模型中表现出这些效果。此外，一种名为NJH的化合物通过激活AMPK/Nrf2/HO-1信号通路和调节与凋亡相关的蛋白质来减轻肾细胞的氧化应激。尚未发现Gaultheria procumbens存在重大安全问题或记录在案的药物相互作用，但进一步研究对于完全了解其潜在益处及其应用是必要的。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 研究发现，紫珠油与其他几种精油一起对某些真菌分离株表现出抗真菌活性。
- AS632和AS633两种制剂均表现出显著的抗炎和抗氧化作用，其中AS632在巨噬细胞中显示出更强的TNF-α抑制作用。
- (6S,9R)-来自Gaultheria procumbens的呕叶醇在体外的人免疫细胞模型中显示出抗炎和抗氧化作用。
- NJH通过激活AMPK/Nrf2/HO-1信号通路和调节与凋亡相关的蛋白质，缓解了NRK-52E细胞中由H2O2诱导的氧化应激。
Frequently asked questions
What is Checkerberry?
Checkerberry (Gaultheria procumbens) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Checkerberry?
4 sourced findings are recorded for Checkerberry; the strongest carries evidence grade D. For example: 研究发现，紫珠油与其他几种精油一起对某些真菌分离株表现出抗真菌活性。
How strong is the evidence for Checkerberry?
The strongest finding for Checkerberry carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Checkerberry safe? What are the side effects?
No major safety issues are recorded for Checkerberry in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Checkerberry interact with medications?
No drug interactions are recorded for Checkerberry in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Checkerberry?
Checkerberry is also known as: Гаультерия лежачая, Gaulthérie couchée.
Is Checkerberry a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Anti-Inflammatory and Antioxidant Effects of (6S,9R)-Vomifoliol from Gaultheria procumbens L.: In Vitro and Ex Vivo Study in Human Immune Cell Models. literature abstract metadata
- T2 Exploring the potential of essential oils against airborne fungi from cultural heritage conservation premises. literature abstract metadata
- T2 Ameliorative Effects of the Neng-Jing-Huo Essential Oil Blend on H2O2-induced Oxidative Stress Injury in NRK-52E Cells via the AMPK/Nrf2/HO-1 Signaling Pathway. literature abstract metadata
- T2 Anti-Inflammatory and Antioxidant Effects of Topical Formulations Containing Plant Extracts, Methylsulfonylmethane, and Peptiskin® in In Vitro Models of Arthritis. literature abstract metadata