Ilex guayusa
Ilex guayusa
Ilex guayusa, a traditional plant from Ecuador, has seen its use and preparation evolve among Kichwa families in Napo province. Traditionally, specific uses are not well-documented; however, modern research indicates that Ilex guayusa leaf extract may improve mood, energy, and cognitive performance, with higher doses potentially enhancing motor-cognitive function but also increasing jitteriness, particularly in women. Scientific evidence suggests that the plant's metabolite profile is influenced by factors such as age and sunlight exposure, impacting various metabolic pathways. An integrated workflow for quantifying chlorogenic acids using HPLC-UV and MS/MS has been developed to enhance structural characterization. No major safety concerns or known drug interactions have been recorded, though further research is warranted to fully understand its potential effects and applications.
- Beste Evidenz
- B
- Warnhinweise
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Nur zur Information. Traditionelle Anwendung bedeutet keine nachgewiesene Wirksamkeit. Evidenz und Sicherheit variieren — siehe die angegebenen Quellen.
Was die Wissenschaft sagt
- Das Blattextrakt von Ilex guayusa verbesserte Laune, Energie und kognitive Leistung bei beiden getesteten Dosen, wobei höhere Dosen das motorische-Kognitionsleistungsvermögen verstärkten, aber bei Frauen Unruhe verursachten.
- Die Studie zeigte an, dass sowohl die Alter der Pflanze als auch ihre Sonneneinstrahlung signifikante Einfluss auf den Metaboliten-Profil der Ilex guayusa Blätter hatten, und beeinflussten die Konzentration verschiedener Metaboliten in verschiedenen Metabolschen Wegen.
- Die Studie entwickelte ein integriertes Arbeitsablaufkonzept für das Profilieren von Chlorogänsäten in Ilex guayusa unter Verwendung HPLC-UV und UPLC-MS/MS, die strukturelle Charakterisierung ohne vollständige Isomer-Quantifizierung verbessern.
- Die Studie zeigte an, dass obwohl einige traditionelle Praktiken bestehen bleiben, die Verbrauch und Zubereitung von Guayusa seit einigen Jahren bei den Kichwa-Familien sich entwickelt haben.
Frequently asked questions
What is Ilex guayusa?
Ilex guayusa (Ilex guayusa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Ilex guayusa?
4 sourced findings are recorded for Ilex guayusa; the strongest carries evidence grade B. For example: Das Blattextrakt von Ilex guayusa verbesserte Laune, Energie und kognitive Leistung bei beiden getesteten Dosen, wobei höhere Dosen das motorische-Kognitionsleistungsvermögen verstärkten, aber bei Frauen Unruhe verursachten.
How strong is the evidence for Ilex guayusa?
The strongest finding for Ilex guayusa carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Ilex guayusa safe? What are the side effects?
No major safety issues are recorded for Ilex guayusa in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Ilex guayusa interact with medications?
No drug interactions are recorded for Ilex guayusa in our sources. This does not rule them out — check with a pharmacist.
Is Ilex guayusa a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Quellen
- T2 Acute, dose-response effects of guayusa leaf extract on mood, cognitive and motor-cognitive performance, and blood pressure, heart rate, and ventricular repolarization. literature abstract metadata
- T2 Integrated HPLC-UV validation and LC-MS/MS optimization with molecular networking and chemometrics for advanced characterization of chlorogenic acids in Ilex guayusa. literature abstract metadata
- T2 Influence of plant age and sunlight exposure on the volatile profile and metabolomic pathways of Ilex guayusa leaves used in the traditional Amazonian beverage. literature abstract metadata
- T2 Socio-cultural components related to the cropping, harvesting, and consumption of guayusa (Ilex guayusa Loes) in Amazonian Kichwa communities. literature abstract metadata