Ilex guayusa
Ilex guayusa
Ilex guayusa, a traditional plant from Ecuador, has seen its use and preparation evolve among Kichwa families in Napo province. Traditionally, specific uses are not well-documented; however, modern research indicates that Ilex guayusa leaf extract may improve mood, energy, and cognitive performance, with higher doses potentially enhancing motor-cognitive function but also increasing jitteriness, particularly in women. Scientific evidence suggests that the plant's metabolite profile is influenced by factors such as age and sunlight exposure, impacting various metabolic pathways. An integrated workflow for quantifying chlorogenic acids using HPLC-UV and MS/MS has been developed to enhance structural characterization. No major safety concerns or known drug interactions have been recorded, though further research is warranted to fully understand its potential effects and applications.
- Meilleure preuve
- B
- Précautions
- —
Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.
Ce que dit la science
- L'extrait de feuille d'Ilex guayusa a amélioré l'humeur, l'énergie et les performances cognitives aux deux doses testées, avec des doses plus élevées renforçant le performance moteur-cognitive mais augmentant l'agitation chez les femmes.
- L'étude a montré que l'âge de la plante et son exposition à la lumière solaire ont significativement influencé le profil métabolique des feuilles d'Ilex guayusa, affectant les niveaux de divers métabolites impliqués dans différentes voies métaboliques.
- L'étude a développé un flux de travail intégré pour le profilage des acides chlorogéniques dans Ilex guayusa en utilisant HPLC-UV et UPLC-MS/MS, améliorant la caractérisation structurelle sans une quantification complète des isomères.
- L'étude a montré que si certaines pratiques traditionnelles persistent, les familles kichwa ont évolué récemment dans leur consommation et préparation de guayusa.
Frequently asked questions
What is Ilex guayusa?
Ilex guayusa (Ilex guayusa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Ilex guayusa?
4 sourced findings are recorded for Ilex guayusa; the strongest carries evidence grade B. For example: L'extrait de feuille d'Ilex guayusa a amélioré l'humeur, l'énergie et les performances cognitives aux deux doses testées, avec des doses plus élevées renforçant le performance moteur-cognitive mais augmentant l'agitation chez les femmes.
How strong is the evidence for Ilex guayusa?
The strongest finding for Ilex guayusa carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Ilex guayusa safe? What are the side effects?
No major safety issues are recorded for Ilex guayusa in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Ilex guayusa interact with medications?
No drug interactions are recorded for Ilex guayusa in our sources. This does not rule them out — check with a pharmacist.
Is Ilex guayusa a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Acute, dose-response effects of guayusa leaf extract on mood, cognitive and motor-cognitive performance, and blood pressure, heart rate, and ventricular repolarization. literature abstract metadata
- T2 Integrated HPLC-UV validation and LC-MS/MS optimization with molecular networking and chemometrics for advanced characterization of chlorogenic acids in Ilex guayusa. literature abstract metadata
- T2 Influence of plant age and sunlight exposure on the volatile profile and metabolomic pathways of Ilex guayusa leaves used in the traditional Amazonian beverage. literature abstract metadata
- T2 Socio-cultural components related to the cropping, harvesting, and consumption of guayusa (Ilex guayusa Loes) in Amazonian Kichwa communities. literature abstract metadata