Heart-leaf Indian madder
Rubia cordifolia
Rubia cordifolia, also known as Indian madder or manjishtha, is a traditional plant primarily used in Ayurvedic and Unani medicine. While its specific uses are not extensively documented, it is traditionally believed to have various therapeutic properties including blood purifying, anti-inflammatory, and skin healing effects. Scientific evidence suggests that Rubia cordifolia has diverse pharmacological activities such as antioxidant, antimicrobial, and hepatoprotective properties. Studies indicate potential benefits in modulating intestinal permeability and alleviating symptoms associated with ulcerative colitis through modulation of the IL-17A/IL-22-C/EBPβ-STAT3 axis. However, due to variations in phytochemical composition among different Rubia species, clinical interchangeability remains uncertain. Safety-wise, no significant adverse effects have been reported for Rubia cordifolia. There are currently no recorded drug interactions associated with its use.
- Beste Evidenz
- D
- Warnhinweise
- —
Nur zur Information. Traditionelle Anwendung bedeutet keine nachgewiesene Wirksamkeit. Evidenz und Sicherheit variieren — siehe die angegebenen Quellen.
Was die Wissenschaft sagt
- The study highlights Rubia cordifolia's diverse traditional uses and modern pharmacological properties including antioxidants, antimicrobials, and hepatoprotectants.
- Diese Bewertung betont die vielfältigen pharmakologischen Aktivitäten der Rubia-Pflanzen, fragt aber nach ihrer klinischen Ersatzbarkeit aufgrund unterschiedlicher Phytochemikalie-Kompositionen.
- RBA hat die signifikant vergrößerten Intestinalpermeabilitätszunahmen durch LPS und TNF-α stark reduziert und beeinflusst die Lokalisierung von Zellulären Tiefenknüpfproteinen in Caco-2-Zellen.
- Selbst zusammengebildete Nanopartikel aus kartoffelgeröstem Rubia cordifolia zeigen eine verbesserte Stabilität und lindern die UC durch Modulation des IL-17A/IL-22-C/EBPβ-STAT3-Achsen.
Frequently asked questions
What is Heart-leaf Indian madder?
Heart-leaf Indian madder (Rubia cordifolia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Heart-leaf Indian madder?
4 sourced findings are recorded for Heart-leaf Indian madder; the strongest carries evidence grade D. For example: The study highlights Rubia cordifolia's diverse traditional uses and modern pharmacological properties including antioxidants, antimicrobials, and hepatoprotectants.
How strong is the evidence for Heart-leaf Indian madder?
The strongest finding for Heart-leaf Indian madder carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Heart-leaf Indian madder safe? What are the side effects?
No major safety issues are recorded for Heart-leaf Indian madder in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Heart-leaf Indian madder interact with medications?
No drug interactions are recorded for Heart-leaf Indian madder in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Heart-leaf Indian madder?
Heart-leaf Indian madder is also known as: Марена сердцелистная, garance indien.
Is Heart-leaf Indian madder a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Quellen
- T2 Therapeutic Potential of Ruberythric Acid in Intestinal Inflammation and Barrier Function Reduction. literature abstract metadata
- T2 Unveiling the Modern Therapeutic Properties and Folk Medicinal Riches of Rubia cordifolia. literature abstract metadata
- T2 A comprehensive review of Rubia medicinal plants: Traditional uses, botany, phytochemistry, and pharmacological activities. literature abstract metadata
- T2 Discovery of self-assembled nanoparticles from Rubia cordifolia L. before and after carbonization and mechanistic study on their targeted therapy for ulcerative colitis. literature abstract metadata