Baikal skullcap
Scutellaria baicalensis
Scutellaria baicalensis, commonly known as Chinese skullcap, originates from traditional Chinese medicine and has a long history of use. Traditionally, it is not specifically documented for any particular uses; however, its active compounds are believed to have various therapeutic effects. Scientific evidence suggests that the flavonoid baicalein, found in Scutellaria baicalensis, may enhance radiosensitivity in certain breast cancer cells and reduce infarct area in acute ischemic stroke models by targeting ROS scavenging and neuroinflammation. Additionally, studies have identified specific genes involved in its biological activities, such as SbGATA6 expression being upregulated by carbon dot treatment. While no major safety issues or drug interactions have been recorded, the current body of research is still limited and further investigation is warranted to fully understand its potential benefits and mechanisms of action.
- Beste Evidenz
- D
- Warnhinweise
- —
Nur zur Information. Traditionelle Anwendung bedeutet keine nachgewiesene Wirksamkeit. Evidenz und Sicherheit variieren — siehe die angegebenen Quellen.
Was die Wissenschaft sagt
- Die Studie identifizierte 25 SbGATA-Gene bei Scutellaria baicalensis und fand heraus, dass die Ausprägung des Gens SbGATA6 durch das Behandeln mit Kohlenstoffpunkten erhöht wurde, während andere Gene eine Abnahme zeigten.
- Baikalein erhöht die Radiosensitivität radioresistenter BR549- und MCF7-R-Mammazelllinien durch Inhibition der Rac1-Aktivität.
- Diese Studie fand heraus, dass eine Nanoplattform, die Baicalein aus Scutellaria baicalensis und Rapamycin kombiniert, den Infarktflächenumfang bei akuter Ischämischer Hirnverletzung durch das Zielempfindliche Absaugen von ROS und die Neuroinflammation reduziert.
- Die Studie zeigte an, dass ein quantitativer Hauptkomponentenanalyse basierend auf Punkten kombiniert mit zweidimensionalen Korrelationspektroskopie von zwei Spuren semi-quantitativ flavonoidische Konzentrationen in Scutellaria baicalensis-Ekstrakten bestimmen kann.
- Die Studie erkannte Metabolitenunterschiede zwischen Scutellaria baicalensis aus verschiedenen geografischen Herkunftsregionen und Spezifikationen mit dem Einsatz von maschinellem Lernen.
Frequently asked questions
What is Baikal skullcap?
Baikal skullcap (Scutellaria baicalensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Baikal skullcap?
5 sourced findings are recorded for Baikal skullcap; the strongest carries evidence grade D. For example: Die Studie identifizierte 25 SbGATA-Gene bei Scutellaria baicalensis und fand heraus, dass die Ausprägung des Gens SbGATA6 durch das Behandeln mit Kohlenstoffpunkten erhöht wurde, während andere Gene eine Abnahme zeigten.
How strong is the evidence for Baikal skullcap?
The strongest finding for Baikal skullcap carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Baikal skullcap safe? What are the side effects?
No major safety issues are recorded for Baikal skullcap in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Baikal skullcap interact with medications?
No drug interactions are recorded for Baikal skullcap in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Baikal skullcap?
Baikal skullcap is also known as: Шлемник байкальский.
Is Baikal skullcap a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Quellen
- T2 Molecularly self-assembled nanoplatforms for targeted ROS-scavenging and neuroinflammation alleviation in acute ischemic stroke. literature abstract metadata
- T2 Baicalein Sensitizes Radioresistant BT549 and MCF7-R Breast Cancer Cells by Modulating Rac1 Signaling. literature abstract metadata
- T2 Genome-Wide Identification and Expression Pattern Analysis of the GATA Gene Family Members in Scutellaria baicalensis Georgi Under Carbon Dot Treatment. literature abstract metadata
- T2 Metabolomics coupled with machine learning highlights metabolite profile differences of Scutellaria baicalensis Georgi from different specifications and geographical origins. literature abstract metadata
- T2 EXPRESS: Two-Trace Two-Dimensional (2T2D) Correlation Spectroscopy with Score-Based Quantitative Principal Component Analysis for the Quantification of Multicomponent Chemical Systems Using Attenuated Total Reflection Fourier Transform Infr literature abstract metadata