Baikal skullcap
Scutellaria baicalensis
Scutellaria baicalensis is a perennial herb rooted in traditional East Asian medicine. It is historically utilized for a wide range of conditions, including fever, dysentery, bacterial infections, cough, diarrhea, hypertension, and jaundice, as well as for sedative, antihistamine, and cardiotonic purposes. Scientific evidence is currently limited to specific laboratory studies, such as research on baicalein enhancing radiosensitivity in certain breast cancer cells and a nanoplatform reducing infarct areas in ischemic stroke models. No major safety issues or notable drug interactions have been recorded in the available data. This information is for educational purposes only.
- Traditionally for
- fever · bacterial infections
- Traditions
- TCM · traditional
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
Traditional use
- fever
- bacterial infections
- cough
- diarrhea
- diuretic
- hypertension
- jaundice
- sedative
- antihistamine
- boils
- cardiotonic
- choleretic
- conjunctivitis
- constipation
- dysentery
What the science says
- The study identified 25 SbGATA genes in Scutellaria baicalensis and found that SbGATA6 expression was upregulated by carbon dot treatment, while other genes showed downregulation.
- Baicalein enhances radiosensitivity in radioresistant BT549 and MCF7-R breast cancer cells by inhibiting Rac1 activity.
- This study found that a nanoplatform combining baicalein from Scutellaria baicalensis and rapamycin reduced infarct area in acute ischemic stroke by targeting ROS scavenging and neuroinflammation.
- The study found that score-based quantitative principal component analysis combined with two-trace two-dimensional correlation spectroscopy can semi-quantitatively determine flavonoid concentrations in Scutellaria baicalensis extracts.
- The study identified metabolite differences between Scutellaria baicalensis from different geographical origins and specifications using machine learning.
Frequently asked questions
What is Baikal skullcap?
Baikal skullcap (Scutellaria baicalensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What is Baikal skullcap traditionally used for?
Traditional sources record Baikal skullcap for: fever, bacterial infections, cough, diarrhea, diuretic, hypertension. This reflects traditional use, not a proven medical treatment.
Which traditions use Baikal skullcap?
Baikal skullcap appears in these traditions in our sources: TCM, traditional.
What does the scientific evidence say about Baikal skullcap?
5 sourced findings are recorded for Baikal skullcap; the strongest carries evidence grade D. For example: The study identified 25 SbGATA genes in Scutellaria baicalensis and found that SbGATA6 expression was upregulated by carbon dot treatment, while other genes showed downregulation.
How strong is the evidence for Baikal skullcap?
The strongest finding for Baikal skullcap carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Baikal skullcap safe? What are the side effects?
No major safety issues are recorded for Baikal skullcap in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Baikal skullcap interact with medications?
No drug interactions are recorded for Baikal skullcap in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Baikal skullcap?
Baikal skullcap is also known as: Шлемник байкальский.
Is Baikal skullcap a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T3 Dr. Duke's Ethnobotanical Database public domain (USDA ARS — attribute Dr. Duke's)
- T2 Molecularly self-assembled nanoplatforms for targeted ROS-scavenging and neuroinflammation alleviation in acute ischemic stroke. literature abstract metadata
- T2 Baicalein Sensitizes Radioresistant BT549 and MCF7-R Breast Cancer Cells by Modulating Rac1 Signaling. literature abstract metadata
- T2 Genome-Wide Identification and Expression Pattern Analysis of the GATA Gene Family Members in Scutellaria baicalensis Georgi Under Carbon Dot Treatment. literature abstract metadata
- T2 Metabolomics coupled with machine learning highlights metabolite profile differences of Scutellaria baicalensis Georgi from different specifications and geographical origins. literature abstract metadata
- T2 EXPRESS: Two-Trace Two-Dimensional (2T2D) Correlation Spectroscopy with Score-Based Quantitative Principal Component Analysis for the Quantification of Multicomponent Chemical Systems Using Attenuated Total Reflection Fourier Transform Infr literature abstract metadata