Baikal skullcap
Scutellaria baicalensis
Scutellaria baicalensis, commonly known as Chinese skullcap, is a traditional herb used in Chinese medicine. Traditionally, it has been employed for various purposes such as treating fever and inflammation, though specific uses are not extensively documented. Scientific evidence suggests potential benefits, including enhancing radiosensitivity in certain breast cancer cells through the inhibition of Rac1 activity, and reducing infarct area in acute ischemic stroke models by targeting ROS scavenging and neuroinflammation. Additionally, studies have identified 25 SbGATA genes in Scutellaria baicalensis, with particular attention to the upregulation of SbGATA6 expression under certain treatments. While no major safety issues or drug interactions have been recorded, these findings are still preliminary and require further investigation.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study identified 25 SbGATA genes in Scutellaria baicalensis and found that SbGATA6 expression was upregulated by carbon dot treatment, while other genes showed downregulation.
- Baicalein enhances radiosensitivity in radioresistant BT549 and MCF7-R breast cancer cells by inhibiting Rac1 activity.
- This study found that a nanoplatform combining baicalein from Scutellaria baicalensis and rapamycin reduced infarct area in acute ischemic stroke by targeting ROS scavenging and neuroinflammation.
- The study found that score-based quantitative principal component analysis combined with two-trace two-dimensional correlation spectroscopy can semi-quantitatively determine flavonoid concentrations in Scutellaria baicalensis extracts.
- The study identified metabolite differences between Scutellaria baicalensis from different geographical origins and specifications using machine learning.
Frequently asked questions
What is Baikal skullcap?
Baikal skullcap (Scutellaria baicalensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Baikal skullcap?
5 sourced findings are recorded for Baikal skullcap; the strongest carries evidence grade D. For example: The study identified 25 SbGATA genes in Scutellaria baicalensis and found that SbGATA6 expression was upregulated by carbon dot treatment, while other genes showed downregulation.
How strong is the evidence for Baikal skullcap?
The strongest finding for Baikal skullcap carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Baikal skullcap safe? What are the side effects?
No major safety issues are recorded for Baikal skullcap in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Baikal skullcap interact with medications?
No drug interactions are recorded for Baikal skullcap in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Baikal skullcap?
Baikal skullcap is also known as: Шлемник байкальский.
Is Baikal skullcap a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Molecularly self-assembled nanoplatforms for targeted ROS-scavenging and neuroinflammation alleviation in acute ischemic stroke. literature abstract metadata
- T2 Baicalein Sensitizes Radioresistant BT549 and MCF7-R Breast Cancer Cells by Modulating Rac1 Signaling. literature abstract metadata
- T2 Genome-Wide Identification and Expression Pattern Analysis of the GATA Gene Family Members in Scutellaria baicalensis Georgi Under Carbon Dot Treatment. literature abstract metadata
- T2 Metabolomics coupled with machine learning highlights metabolite profile differences of Scutellaria baicalensis Georgi from different specifications and geographical origins. literature abstract metadata
- T2 EXPRESS: Two-Trace Two-Dimensional (2T2D) Correlation Spectroscopy with Score-Based Quantitative Principal Component Analysis for the Quantification of Multicomponent Chemical Systems Using Attenuated Total Reflection Fourier Transform Infr literature abstract metadata