Anglo-Japanese yew
Taxus ×media
Taxus ×media, also known as yew hybrid, is a traditional medicine with origins in East Asia. While it has not been traditionally used for any specific medicinal purposes, studies have shown promise in its potential applications. Research indicates that the plant contains enzymes involved in paclitaxel biosynthesis, including novel C1β-hydroxylase and dioxygenase activities, which could be significant for cancer treatment research. Five new 14-oxygenated taxanes were isolated from Taxus ×media cell cultures, one of which demonstrated potential cytotoxic activity against cervical carcinoma cells. The study also developed a cellulose-based material that can selectively enrich paclitaxel from plant extracts. Currently, there is no recorded evidence of major safety issues or drug interactions associated with this plant.
- Mejor evidencia
- D
- Precauciones
- —
Solo información. El uso tradicional no significa eficacia probada. La evidencia y la seguridad varían — consulte las fuentes citadas.
Lo que dice la ciencia
- El estudio reporta la descubrimiento y caracterización de enzimas implicadas en la biosíntesis de taxanos, incluyendo una nueva C1β-hidroxilasa y una dioxigenasa.
- El estudio identificó y caracterizó una lipoxigenasa 13 (TmLOX13) en Taxus media, vinculándola con la biosíntesis de paclitaxel.
- Se isolataron cinco nuevos taxanos oxigenados del lado catorce de las culturas celulares de Taxus × media y uno mostró actividad citotóxica potencial.
- El estudio desarrolló un material dual-responsivo capaz de enriquecer selectivamente la paclitaxel a partir de extractos vegetales.
Frequently asked questions
What is Anglo-Japanese yew?
Anglo-Japanese yew (Taxus ×media) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Anglo-Japanese yew?
4 sourced findings are recorded for Anglo-Japanese yew; the strongest carries evidence grade D. For example: El estudio reporta la descubrimiento y caracterización de enzimas implicadas en la biosíntesis de taxanos, incluyendo una nueva C1β-hidroxilasa y una dioxigenasa.
How strong is the evidence for Anglo-Japanese yew?
The strongest finding for Anglo-Japanese yew carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Anglo-Japanese yew safe? What are the side effects?
No major safety issues are recorded for Anglo-Japanese yew in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Anglo-Japanese yew interact with medications?
No drug interactions are recorded for Anglo-Japanese yew in our sources. This does not rule them out — check with a pharmacist.
Is Anglo-Japanese yew a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Fuentes
- T2 Cellulose-based molecularly imprinted core-shell microspheres with dual environment responsiveness for specific recognition and enrichment of paclitaxel. literature abstract metadata
- T2 Five new 14-oxygenated taxanes from the cell cultures of Taxus × media. literature abstract metadata
- T2 Novel α-KG/Fe(II)-Dependent Dioxygenases Catalyzing C1β-Hydroxylation and Construction of 5/7/6-Skeleton of Highly Oxygenated Taxoids. literature abstract metadata
- T2 A new 13-lipoxygenase from Taxus media callus is functionally linked to paclitaxel biosynthesis. literature abstract metadata