Anglo-Japanese yew
Taxus ×media
Taxus ×media is a hybrid yew tree, traditionally not used in any known medicinal practices. Scientific research has identified enzymes involved in taxane biosynthesis within this plant, including a novel C1β-hydroxylase and a dioxygenase. Additionally, five new 14-oxygenated taxanes were isolated from cell cultures of Taxus ×media, one of which demonstrated potential cytotoxic activity. The study also developed a dual-responsive material for selectively enriching paclitaxel from plant extracts. To date, no major safety concerns or drug interactions have been recorded regarding this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study reports the discovery and characterization of enzymes involved in the biosynthesis of taxanes, including a novel C1β-hydroxylase and a dioxygenase.
- The study identified and characterized a 13-Lipoxygenase (TmLOX13) in Taxus media, linking it to paclitaxel biosynthesis.
- Five new 14-oxygenated taxanes were isolated from Taxus × media cell cultures, and one showed potential cytotoxic activity.
- The study developed a dual-responsive material capable of selectively enriching paclitaxel from plant extracts.
Frequently asked questions
What is Anglo-Japanese yew?
Anglo-Japanese yew (Taxus ×media) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Anglo-Japanese yew?
4 sourced findings are recorded for Anglo-Japanese yew; the strongest carries evidence grade D. For example: The study reports the discovery and characterization of enzymes involved in the biosynthesis of taxanes, including a novel C1β-hydroxylase and a dioxygenase.
How strong is the evidence for Anglo-Japanese yew?
The strongest finding for Anglo-Japanese yew carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Anglo-Japanese yew safe? What are the side effects?
No major safety issues are recorded for Anglo-Japanese yew in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Anglo-Japanese yew interact with medications?
No drug interactions are recorded for Anglo-Japanese yew in our sources. This does not rule them out — check with a pharmacist.
Is Anglo-Japanese yew a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Cellulose-based molecularly imprinted core-shell microspheres with dual environment responsiveness for specific recognition and enrichment of paclitaxel. literature abstract metadata
- T2 Five new 14-oxygenated taxanes from the cell cultures of Taxus × media. literature abstract metadata
- T2 Novel α-KG/Fe(II)-Dependent Dioxygenases Catalyzing C1β-Hydroxylation and Construction of 5/7/6-Skeleton of Highly Oxygenated Taxoids. literature abstract metadata
- T2 A new 13-lipoxygenase from Taxus media callus is functionally linked to paclitaxel biosynthesis. literature abstract metadata