Feuilles cotaire

Cissus verticillata · Possum grape

Cissus verticillata, a traditional medicine plant, is primarily found in tropical regions of Africa. While it has not been traditionally used for specific medicinal purposes, studies have shown promising results. In vitro research indicates that Cissus verticillata leaf extract may reduce the production of AGEs and ROS, suggesting potential benefits against oxidative stress. Additionally, a trypsin inhibitor from its leaves, known as CvLTI, demonstrated antibacterial, hemolytic, and immunomodulatory effects. Further studies in mice indicated that CVE treatment improved memory deficits and increased BDNF levels in the hippocampus of high-fat diet-fed animals. In another study, CVE treatment reduced oxidative and ischemic stress-induced neuronal damage by mitigating inflammation and MAPK phosphorylation. Safety data for Cissus verticillata is currently limited but does not indicate any major issues. There are also no recorded drug interactions at this time.

En bref
Meilleure preuve
D
Précautions

Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.

Ce que dit la science

  • l'extrait de feuilles de Cissus verticillata a réduit la production d'AGEs et de ROS in vitro. D PMID
  • CvLTI, un inhibiteur de trypson issu des feuilles de Cissus verticillata, a montré des effets antibactériens, hémolytiques et immunomodulateurs. D PMID
  • Le traitement par CVE a amélioré les déficits de mémoire et augmenté les niveaux de BDNF chez les souris nourries avec une alimentation riche en graisses. D PMID
  • Le traitement CVE a réduit les dommages neuronaux induits par le stress oxydatif et ischémique chez les cellules et les gerbilles en atténuant l'inflammation et la phosphorylation des MAPK. D PMID

Frequently asked questions

What is Feuilles cotaire?

Feuilles cotaire (Cissus verticillata) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Feuilles cotaire?

4 sourced findings are recorded for Feuilles cotaire; the strongest carries evidence grade D. For example: l'extrait de feuilles de Cissus verticillata a réduit la production d'AGEs et de ROS in vitro.

How strong is the evidence for Feuilles cotaire?

The strongest finding for Feuilles cotaire carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Feuilles cotaire safe? What are the side effects?

No major safety issues are recorded for Feuilles cotaire in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Feuilles cotaire interact with medications?

No drug interactions are recorded for Feuilles cotaire in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Feuilles cotaire?

Feuilles cotaire is also known as: Possum grape.

Is Feuilles cotaire a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Cissus verticillata Extract Decreases Neuronal Damage Induced by Oxidative Stress in HT22 Cells and Ischemia in Gerbils by Reducing the Inflammation and Phosphorylation of MAPKs. literature abstract metadata
  2. T2 Extracts from the Leaves of Cissus verticillata Ameliorate High-Fat Diet-Induced Memory Deficits in Mice. literature abstract metadata
  3. T2 A Novel Trypsin Inhibitor With Immunomodulatory Activity From the Leaves of Cissus verticillata subsp. verticillata (L.) Nicolson & C.E. Jarvis. literature abstract metadata
  4. T2 Cissus verticillata Leaf Extract Decreases the Production of AGEs and ROS In Vitro. literature abstract metadata