Large-flower motherwort
Leonurus macranthus
Leonurus macranthus is a plant traditionally used in East Asian medicine but lacks specific recorded traditional uses. Scientific evidence suggests that it contains polyoxygenated labdane diterpenoids, some of which show potential for inhibiting nitric oxide production in microglial cells. Additionally, HGK nanosuspensions derived from Leonurus macranthus have demonstrated enhanced antitumor efficacy against breast cancer cells both in vitro and in vivo, though the broader applicability of this finding remains to be fully explored. The plant is found in areas rich in forest biodiversity, particularly on algific talus slopes in South Korea. Safety concerns are currently minimal, with no major issues recorded; similarly, there are no reported drug interactions at present.
- Meilleure preuve
- D
- Précautions
- —
Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.
Ce que dit la science
- Twenty new polyoxygenated labdane diterpenoids were isolated from Leonurus macranthus, and some showed inhibition of nitric oxide production in microglial cells.
- Les nanosolutions HGK ont montré une cytopathicité accrue contre les cellules du cancer du sein in vitro et une activité antitumorale in vivo comparables à celle de la paclitaxel.
- L'étude a examiné 25 pentes algifères au sud de la Corée et a découvert un total de 1 052 taxons de plantes vasculaires.
- Les zones d'abandon agricole croissant se chevauchaient avec les domaines de distribution des espèces végétales qui étaient précédemment communes mais sont maintenant menacées au Japon.
Frequently asked questions
What is Large-flower motherwort?
Large-flower motherwort (Leonurus macranthus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Large-flower motherwort?
4 sourced findings are recorded for Large-flower motherwort; the strongest carries evidence grade D. For example: Twenty new polyoxygenated labdane diterpenoids were isolated from Leonurus macranthus, and some showed inhibition of nitric oxide production in microglial cells.
How strong is the evidence for Large-flower motherwort?
The strongest finding for Large-flower motherwort carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Large-flower motherwort safe? What are the side effects?
No major safety issues are recorded for Large-flower motherwort in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Large-flower motherwort interact with medications?
No drug interactions are recorded for Large-flower motherwort in our sources. This does not rule them out — check with a pharmacist.
Is Large-flower motherwort a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Areas of increasing agricultural abandonment overlap the distribution of previously common, currently threatened plant species. literature abstract metadata
- T2 Anti-inflammatory Labdane Diterpenoids from Leonurus macranthus. literature abstract metadata
- T2 Preparation of hydroxy genkwanin nanosuspensions and their enhanced antitumor efficacy against breast cancer. literature abstract metadata
- T2 Floristic inventory and distribution characteristics of algific talus slopes in a specific area of forest biodiversity in South Korea. literature abstract metadata