Dompte-venin
Vincetoxicum hirundinaria · German ipecac
Vincetoxicum hirundinaria is a plant traditionally not used in any known medicinal practices. Scientific evidence has shown that extracts from this plant exhibit an inhibitory effect on IL-6 release, with activity observed at 3.6 μg/mL. However, the strength of this finding is limited by the small scale and specific conditions under which the study was conducted. Genetic studies indicate local inbreeding and regional isolation patterns for related species, suggesting limited dispersal ability despite colonization of northern Europe post-glacially. Extracts from Vincetoxicum hirundinaria have been found to induce DNA damage as measured by the comet assay, with varying effects on micronuclei and sister chromatid exchange; these findings are preliminary and require further investigation. No major safety issues or drug interactions have been recorded for this plant, but caution is advised due to its potential genotoxicity.
- Meilleure preuve
- D
- Précautions
- —
Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.
Ce que dit la science
- Vincetoxicum hirundinaria a montré un effet distinct inhibiteur sur la libération d'IL-6 dans les PBMCs à une concentration de 3,6 μg/mL.
- L'étude a révélé des niveaux significatifs d'inbreeding local et des modèles d'isolement par distance régional pour la mouche du foie Contarinia vincetoxici, suggérant une capacité de dispersion limitée malgré sa colonisation de l'Europe septentrionale post-glaciaire.
- Le dérèglement génétique plutôt que des compromis ont limité l'adaptation de L. equestris à de nouveaux hôtes au cours de 20 générations.
- Tous les extraits ont provoqué des dommages au ADN selon l'assay comète, avec des réponses variées.
Frequently asked questions
What is Dompte-venin?
Dompte-venin (Vincetoxicum hirundinaria) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Dompte-venin?
4 sourced findings are recorded for Dompte-venin; the strongest carries evidence grade D. For example: Vincetoxicum hirundinaria a montré un effet distinct inhibiteur sur la libération d'IL-6 dans les PBMCs à une concentration de 3,6 μg/mL.
How strong is the evidence for Dompte-venin?
The strongest finding for Dompte-venin carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Dompte-venin safe? What are the side effects?
No major safety issues are recorded for Dompte-venin in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Dompte-venin interact with medications?
No drug interactions are recorded for Dompte-venin in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Dompte-venin?
Dompte-venin is also known as: German ipecac, Ластовень ласточкин.
Is Dompte-venin a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Genetic drift precluded adaptation of an insect seed predator to a novel host plant in a long-term selection experiment. literature abstract metadata
- T2 Genotoxic properties of Betonica officinalis, Gratiola officinalis, Vincetoxicum luteum and Vincetoxicum hirundinaria extracts. literature abstract metadata
- T2 Post-glacial colonization of the Fennoscandian coast by a plant parasitic insect with an unusual life history. literature abstract metadata
- T2 Plants and their uses in dermatological recipes of the Receptarium of Burkhard III von Hallwyl from 16th century Switzerland - Data mining a historical text and preliminary in vitro screening. literature abstract metadata