Allophylus cobbe
Allophylus cobbe
Allophylus cobbe 是一种传统上在非洲和亚洲部分地区用于各种民间医学实践的植物。尽管其具体的传统用途尚未详细记录，但已对其潜在的健康益处进行了研究。科学证据表明，Allophylus cobbe 叶提取物可能对某些癌细胞（特别是 HepG2 细胞）表现出细胞毒性效应，IC50 值低于 100 μg/mL。此外，该植物还显示出抗氧化和弱抗癌活性，对抗前列腺癌细胞系而不影响正常细胞；然而，需要进一步研究来确认这些发现。从 Allophylus cobbe 叶提取物中合成的银纳米颗粒与传统抗生素结合使用时，对多种人类病原性细菌表现出增强的抗菌和抗生物膜活性。还从植物的根和枝条中分离出一种新的生育三烯醇 5-羟基-8-甲基生育三烯醇。迄今为止尚未发现重大安全问题或记录在案的药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- Allophylus cobbe叶片提取物对HepG2细胞表现出细胞毒性，IC50值<100 μg/mL。
- 研究发现，Allophylus cobbe叶片提取物显示出潜在的抗氧化活性和对前列腺癌细胞系的弱抗肿瘤作用，而不影响正常细胞，尽管仍需进一步的研究。
- 研究发现，使用阿洛菲鲁斯·科比（Allophylus cobbe）叶片提取物合成的银纳米颗粒与传统抗生素联合使用时，对多种人类病原性细菌显示出增强的抗菌和抗生物膜活性。
- 一种新的三萜醇——5-羟基-8-甲基三萜醇，已从Allophylus cobbe的根部和枝条中分离出来。
- 研究发现，从Allophylus cobbe提取的物质对细菌和真菌表现出不同程度的抗菌活性，并观察到一些显著抑制作用。
Frequently asked questions
What is Allophylus cobbe?
Allophylus cobbe (Allophylus cobbe) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Allophylus cobbe?
5 sourced findings are recorded for Allophylus cobbe; the strongest carries evidence grade D. For example: Allophylus cobbe叶片提取物对HepG2细胞表现出细胞毒性，IC50值<100 μg/mL。
How strong is the evidence for Allophylus cobbe?
The strongest finding for Allophylus cobbe carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Allophylus cobbe safe? What are the side effects?
No major safety issues are recorded for Allophylus cobbe in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Allophylus cobbe interact with medications?
No drug interactions are recorded for Allophylus cobbe in our sources. This does not rule them out — check with a pharmacist.
Is Allophylus cobbe a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 In vitro antimicrobial and brine shrimp lethality of Allophylus cobbe L. literature abstract metadata
- T2 Enhanced antibacterial and anti-biofilm activities of silver nanoparticles against Gram-negative and Gram-positive bacteria. literature abstract metadata
- T2 Evaluation of in vitro antioxidant and anticancer activity of Allophylus cobbe leaf extracts on DU-145 and PC-3 human prostate cancer cell lines. literature abstract metadata
- T2 A new tocotrienol from the roots and branches of Allophylus cobbe (L.) Raeusch (Sapindaceae). literature abstract metadata
- T2 Cytotoxicity against Human Hepatocellular Carcinoma (HepG2) Cells and Anti-Oxidant Activity of Selected Endemic or Medicinal Plants in Sri Lanka. literature abstract metadata