Gigantic Angelica
Angelica gigas
Angelica gigas 是一种传统上用于韩国医学的植物，但尚未记录其特定的传统用途。科学证据表明，这种草本植物可能会对肝脏造成损害，与其他草本植物一样，尽管这些发现得到了有限的细胞和分子验证的支持。从 Angelica gigas 中提取的化合物 decursin 显示出抑制肥大细胞激活并减少由 IgE 引起的过敏反应在小鼠中的潜力。此外，JI-CJ002 与 dabrafenib 的组合在黑色素瘤中表现出增强的抗肿瘤活性，通过下调 B7-H3 表达。迄今为止尚未发现重大安全问题或记录的药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 该研究使用了超高效液相色谱法（UHPLC）和RWR网络分析来预测天名精提取物引起的潜在肝损伤，并通过细胞和分子验证进行支持。
- The combination of JI-CJ002 with dabrafenib showed enhanced antitumor activity in melanoma by downregulating B7-H3 expression.
- 去甲乌药碱抑制肥大细胞活化并减少小鼠IgE介导的过敏反应。
- CGAC 正常化了因去势诱导的骨重塑停滞状态，并在去势小鼠中恢复了生理性重塑，没有明确的剂量或治疗建议。
Frequently asked questions
What is Gigantic Angelica?
Gigantic Angelica (Angelica gigas) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Gigantic Angelica?
4 sourced findings are recorded for Gigantic Angelica; the strongest carries evidence grade D. For example: 该研究使用了超高效液相色谱法（UHPLC）和RWR网络分析来预测天名精提取物引起的潜在肝损伤，并通过细胞和分子验证进行支持。
How strong is the evidence for Gigantic Angelica?
The strongest finding for Gigantic Angelica carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Gigantic Angelica safe? What are the side effects?
No major safety issues are recorded for Gigantic Angelica in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Gigantic Angelica interact with medications?
No drug interactions are recorded for Gigantic Angelica in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Gigantic Angelica?
Gigantic Angelica is also known as: Дудник гигантский, Angélique géante.
Is Gigantic Angelica a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Combining UHPLC profiling and random walk network-based in vitro analysis to predict herb-induced liver injury. literature abstract metadata
- T2 Decursin, a bioactive compound from Angelica gigas, suppresses mast cell activation by targeting Fyn kinase and attenuates IgE-mediated anaphylactic responses in mice. literature abstract metadata
- T2 JI-CJ002 and Dabrafenib Combination Enhances Antitumor Activity in Melanoma Associated With the Downregulation of B7-H3. literature abstract metadata
- T2 A Standard Herbal Formula, CGAC, Attenuates Bone Loss by Normalizing Low-Bone Turnover Stagnation in an Orchiectomy-Induced Mouse Model. literature abstract metadata