Gigantic Angelica
Angelica gigas
Angelica gigas 是一种传统用于韩国医学的植物，但其特定药用用途尚未广泛记录。科学证据表明，其提取物可能引起肝损伤，这得到了细胞和分子验证研究的支持。CGAC，源自 Angelica gigas，被发现可以正常化去势诱导的小鼠骨重塑，而没有明确的剂量信息。此外，JI-CJ002 与 dabrafenib 的组合在黑色素瘤模型中通过下调 B7-H3 表达增强了抗肿瘤活性。Decursin 来自 Angelica gigas 抑制了小鼠的肥大细胞激活并减少了 IgE 介导的过敏反应，表明其潜在的抗炎作用。尚未发现该植物的重大安全问题或记录的药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 该研究使用了超高效液相色谱法（UHPLC）和RWR网络分析来预测天名精提取物引起的潜在肝损伤，并通过细胞和分子验证进行支持。
- JI-CJ002 与 dabrafenib 的组合通过下调 B7-H3 表达，在黑色素瘤中显示出增强的抗肿瘤活性。
- 去甲乌药碱抑制肥大细胞活化并减少小鼠IgE介导的过敏反应。
- CGAC 正常化了因去势诱导的骨重塑停滞状态，并在去势小鼠中恢复了生理性重塑，没有明确的剂量或治疗建议。
Frequently asked questions
What is Gigantic Angelica?
Gigantic Angelica (Angelica gigas) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Gigantic Angelica?
4 sourced findings are recorded for Gigantic Angelica; the strongest carries evidence grade D. For example: 该研究使用了超高效液相色谱法（UHPLC）和RWR网络分析来预测天名精提取物引起的潜在肝损伤，并通过细胞和分子验证进行支持。
How strong is the evidence for Gigantic Angelica?
The strongest finding for Gigantic Angelica carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Gigantic Angelica safe? What are the side effects?
No major safety issues are recorded for Gigantic Angelica in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Gigantic Angelica interact with medications?
No drug interactions are recorded for Gigantic Angelica in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Gigantic Angelica?
Gigantic Angelica is also known as: Дудник гигантский, Angélique géante.
Is Gigantic Angelica a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Combining UHPLC profiling and random walk network-based in vitro analysis to predict herb-induced liver injury. literature abstract metadata
- T2 Decursin, a bioactive compound from Angelica gigas, suppresses mast cell activation by targeting Fyn kinase and attenuates IgE-mediated anaphylactic responses in mice. literature abstract metadata
- T2 JI-CJ002 and Dabrafenib Combination Enhances Antitumor Activity in Melanoma Associated With the Downregulation of B7-H3. literature abstract metadata
- T2 A Standard Herbal Formula, CGAC, Attenuates Bone Loss by Normalizing Low-Bone Turnover Stagnation in an Orchiectomy-Induced Mouse Model. literature abstract metadata