Arctium
Arctium
刺阿卡提乌姆（刺阿卡提乌姆拉帕塔林），是一种传统药草，在各种民间实践中被使用。尽管其具体用途在传统医学中没有很好地记录，但科学研究表明它具有潜在的好处。研究表明，刺阿卡提乌姆中的化合物阿卡提因可以通过抑制软骨细胞的焦亡来缓解骨关节炎疼痛，并可能通过针对多种分子途径对不同类型的乳腺癌产生抗肿瘤作用。此外，ALEO（刺阿卡提乌姆乙醇提取物）在体外显示出强大的抗菌活性，对抗世界卫生组织优先病原体具有显著效果。阿卡提因还通过调节S100A8/A9/NOX/NF-κB信号通路中的三羧酸循环和氧化磷酸化损伤来改善肾功能并减少纤维化。没有记录到主要的安全问题或药物相互作用，但需要进一步研究以全面了解其疗效和潜在应用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 从刺儿菜中提取的阿卡提苷通过POU2F1/GRB10轴抑制软骨细胞焦亡从而缓解骨关节炎疼痛。
- ALEO 在体外对多种世卫组织优先病原体显示出强大的抗菌活性。
- 在不同类型的乳腺癌体内外模型中，arctigenin通过靶向多个分子途径显示了抗癌效果。
- ATG 改善肾功能并减少纤维化，通过调节 TCA 循环和氧化磷酸化损伤的 S100A8/A9/NOX/NF-κB 信号通路。
- 从毛刺牛蒡根中提取的AT未表现出急性或亚急性的毒性，并在小鼠中显示出抗炎作用。
- 添加脱脂牛蒡籽粉的木糖醇饼干与木糖醇对照饼干相比，可溶性膳食纤维含量相当，并保持了良好的感官质量。
Frequently asked questions
What is Arctium?
Arctium (Arctium) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Arctium?
6 sourced findings are recorded for Arctium; the strongest carries evidence grade D. For example: 从刺儿菜中提取的阿卡提苷通过POU2F1/GRB10轴抑制软骨细胞焦亡从而缓解骨关节炎疼痛。
How strong is the evidence for Arctium?
The strongest finding for Arctium carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Arctium safe? What are the side effects?
No major safety issues are recorded for Arctium in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Arctium interact with medications?
No drug interactions are recorded for Arctium in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Arctium?
Arctium is also known as: Лопух, Bardane.
Is Arctium a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Effects of Gingerbread Cookie Enrichment with Native and Supercritical CO2-Defatted Burdock Seeds. literature abstract metadata
- T2 In silico and in vitro assessment of antimicrobial activity of Arctium lappa L. leaf and flower essential oil against WHO priority pathogens. literature abstract metadata
- T2 Preliminary Study on the Mechanism of Arctigenin in Alleviating Osteoarthritis Pain by Suppressing Chondrocyte Pyroptosis: The Potential Role of the POU2F1/GRB10 Axis. literature abstract metadata
- T2 Elucidating the therapeutic efficacy and mechanisms of arctigenin in ameliorating renal fibrosis: a combined transcriptomic and proteomic study. literature abstract metadata
- T2 Arctigenin Suppresses Breast Cancer Growth In Vitro and In Vivo Through Subtype-Specific Multi-Targeting Activity. literature abstract metadata
- T2 CO2-Extract-Based Phytopreparation from Arctium tomentosum Mill. Root Exhibits No Acute and Subacute Toxicity and Suppresses Xylene-Induced Ear Edema and LPS-Induced Acute Inflammation in Mice. literature abstract metadata