Arctium
Arctium
Arctium，包括如Arctium lappa（普通刺儿菜）和Arctium tomentosum（绒毛刺儿菜）等物种，是一种传统药草植物，其根部植根于各种草本实践。传统上用于治疗皮肤状况、头发生长问题和消化问题，但具体用途因文化而异。科学证据表明，A. lappa 中发现的arctigenin 可能通过POU2F1/GRB10 轴抑制软骨细胞的焦亡，从而减轻骨关节炎疼痛，显示出潜在的抗炎益处。此外，Arctium lappa 乙醇提取物（ALEO）在体外对多种世界卫生组织优先病原体表现出强大的抗菌活性。来自 Arctium tomentosum 根的 AT 在小鼠模型中未显示急性或亚急性毒性，并且具有抗炎作用。在安全性方面，目前没有记录到使用这种植物的重大问题。也没有报告有显著的药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 从刺儿菜中提取的阿卡提苷通过POU2F1/GRB10轴抑制软骨细胞焦亡从而缓解骨关节炎疼痛。
- ALEO 在体外对多种世卫组织优先病原体显示出强大的抗菌活性。
- 在不同类型的乳腺癌体内外模型中，arctigenin通过靶向多个分子途径显示了抗癌效果。
- ATG 改善肾功能并减少纤维化，通过调节 TCA 循环和氧化磷酸化损伤的 S100A8/A9/NOX/NF-κB 信号通路。
- 从毛刺牛蒡根中提取的AT未表现出急性或亚急性的毒性，并在小鼠中显示出抗炎作用。
- 添加脱脂牛蒡籽粉的木糖醇饼干与木糖醇对照饼干相比，可溶性膳食纤维含量相当，并保持了良好的感官质量。
Frequently asked questions
What is Arctium?
Arctium (Arctium) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Arctium?
6 sourced findings are recorded for Arctium; the strongest carries evidence grade D. For example: 从刺儿菜中提取的阿卡提苷通过POU2F1/GRB10轴抑制软骨细胞焦亡从而缓解骨关节炎疼痛。
How strong is the evidence for Arctium?
The strongest finding for Arctium carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Arctium safe? What are the side effects?
No major safety issues are recorded for Arctium in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Arctium interact with medications?
No drug interactions are recorded for Arctium in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Arctium?
Arctium is also known as: Лопух, Bardane.
Is Arctium a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Effects of Gingerbread Cookie Enrichment with Native and Supercritical CO2-Defatted Burdock Seeds. literature abstract metadata
- T2 In silico and in vitro assessment of antimicrobial activity of Arctium lappa L. leaf and flower essential oil against WHO priority pathogens. literature abstract metadata
- T2 Preliminary Study on the Mechanism of Arctigenin in Alleviating Osteoarthritis Pain by Suppressing Chondrocyte Pyroptosis: The Potential Role of the POU2F1/GRB10 Axis. literature abstract metadata
- T2 Elucidating the therapeutic efficacy and mechanisms of arctigenin in ameliorating renal fibrosis: a combined transcriptomic and proteomic study. literature abstract metadata
- T2 Arctigenin Suppresses Breast Cancer Growth In Vitro and In Vivo Through Subtype-Specific Multi-Targeting Activity. literature abstract metadata
- T2 CO2-Extract-Based Phytopreparation from Arctium tomentosum Mill. Root Exhibits No Acute and Subacute Toxicity and Suppresses Xylene-Induced Ear Edema and LPS-Induced Acute Inflammation in Mice. literature abstract metadata