Aspidosperma
Aspidosperma
阿斯皮多瑟拉是一种传统上不与任何特定的医学用途相关联的植物，在已知的历史或文化实践中。科学研究集中在它的化学成分上，实现了对各种碱基如bisleuconothine A、bousigonine B、(-)-aspidospermidine和(+)-quebrachamine的选择性手性全合成。此外，研究表明阿斯皮多瑟拉subincanum的己烷-乙酸酯（HE-GL）萃取物表现出对Xanthomonas citri的强大抗菌活性，而HE-GL和HE-甘油（HE-GS）均显示出中等程度的乙酰胆碱酯酶抑制作用。这些发现表明其在抗菌和神经化学方面具有潜在应用价值，但需要进一步研究以确认其有效性。没有记录到阿斯皮多瑟拉的重大安全问题或药物相互作用，这表明它在适当处理时可以使用而不会带来显著风险。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 研究实现了对bishleuconothine A和bousigonine B的对映选择性全合成，并重新确定了它们的绝对立体化学。
- The study achieved a collective asymmetric synthesis of 11 aspidosperma indole alkaloids and a formal synthesis of (-)-deoxoapodine using a [3.3.1]-bicyclic ring system construction and a pentacyclic framework installation.
- 该研究实现了(-)-阿斯匹多佩尔米德和(+)-奎布拉卡明的对映选择性全合成，使用手性锂胺烷基化。
- 来自Aspidosperma subincanum的HE-GL对Xanthomonas citri显示出强烈的抗菌活性，而HE-GL和HE-GS均抑制了乙酰胆碱酯酶活性。
Frequently asked questions
What is Aspidosperma?
Aspidosperma (Aspidosperma) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Aspidosperma?
4 sourced findings are recorded for Aspidosperma; the strongest carries evidence grade D. For example: 研究实现了对bishleuconothine A和bousigonine B的对映选择性全合成，并重新确定了它们的绝对立体化学。
How strong is the evidence for Aspidosperma?
The strongest finding for Aspidosperma carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Aspidosperma safe? What are the side effects?
No major safety issues are recorded for Aspidosperma in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Aspidosperma interact with medications?
No drug interactions are recorded for Aspidosperma in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Aspidosperma?
Aspidosperma is also known as: Аспидосперма.
Is Aspidosperma a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Divergent Enantioselective Total Synthesis of Aspidosperma Indole Alkaloids. literature abstract metadata
- T2 Enantioselective Total Syntheses of Bisleuconothine A and Bousigonine B. literature abstract metadata
- T2 Sesquiterpene-rich n-hexane extracts from Aspidosperma subincanum Mart.: anti-Xanthomonas citri activity, acetylcholinesterase inhibition and insights into molecular docking. literature abstract metadata
- T2 Enantioselective Synthesis of (-)-Aspidospermidine and (+)-Quebrachamine via Chiral Lithium Amide Alkylation of Alkynylacetic Acids. literature abstract metadata