Aspidosperma
Aspidosperma
Aspidosperma 是一种传统上在南美洲，特别是巴西发现的植物属。尽管其传统的医学用途没有很好地记录下来，但研究集中在从这些植物中合成和表征吲哚生物碱。已经实现了对几种 Aspidosperma 吲哚生物碱的立体选择性全合成，包括 bisleuconothine A、bousigonine B、(-)-aspidospermidine 和 (+)-quebrachamine。这些研究还报告了使用 [3.3.1]-bicyclic 环系构建和五环框架安装合成了 11 种 Aspidosperma 吲哚生物碱。值得注意的是，Aspidosperma subincanum 的提取物对 Xanthomonas citri 显示出强烈的抗菌活性，而 HE-GL 和 HE-GS 抑制了乙酰胆碱酯酶。到目前为止，这些化合物没有记录到主要的安全问题或药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 研究实现了对bishleuconothine A和bousigonine B的对映选择性全合成，并重新确定了它们的绝对立体化学。
- 该研究实现了对11种aspidosperma来源的吲哚生物碱进行集体不对称合成，并利用[3.3.1]双环系统构建和五环框架安装完成了(-)-deoxoapodine的正式合成。
- 该研究实现了(-)-阿斯匹多佩尔米德和(+)-奎布拉卡明的对映选择性全合成，使用手性锂胺烷基化。
- 来自Aspidosperma subincanum的HE-GL对Xanthomonas citri显示出强烈的抗菌活性，而HE-GL和HE-GS均抑制了乙酰胆碱酯酶活性。
Frequently asked questions
What is Aspidosperma?
Aspidosperma (Aspidosperma) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Aspidosperma?
4 sourced findings are recorded for Aspidosperma; the strongest carries evidence grade D. For example: 研究实现了对bishleuconothine A和bousigonine B的对映选择性全合成，并重新确定了它们的绝对立体化学。
How strong is the evidence for Aspidosperma?
The strongest finding for Aspidosperma carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Aspidosperma safe? What are the side effects?
No major safety issues are recorded for Aspidosperma in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Aspidosperma interact with medications?
No drug interactions are recorded for Aspidosperma in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Aspidosperma?
Aspidosperma is also known as: Аспидосперма.
Is Aspidosperma a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Divergent Enantioselective Total Synthesis of Aspidosperma Indole Alkaloids. literature abstract metadata
- T2 Enantioselective Total Syntheses of Bisleuconothine A and Bousigonine B. literature abstract metadata
- T2 Sesquiterpene-rich n-hexane extracts from Aspidosperma subincanum Mart.: anti-Xanthomonas citri activity, acetylcholinesterase inhibition and insights into molecular docking. literature abstract metadata
- T2 Enantioselective Synthesis of (-)-Aspidospermidine and (+)-Quebrachamine via Chiral Lithium Amide Alkylation of Alkynylacetic Acids. literature abstract metadata