Aspidosperma
Aspidosperma
Aspidosperma is a genus of plants traditionally found in South America, particularly in Brazil. While its traditional medicinal uses are not well-documented, studies have focused on synthesizing and characterizing indole alkaloids from these plants. Research has achieved enantioselective total syntheses of several aspidosperma indole alkaloids, including bisleuconothine A, bousigonine B, (-)-aspidospermidine, and (+)-quebrachamine. These studies have also reported the synthesis of 11 aspidosperma indole alkaloids using a [3.3.1]-bicyclic ring system construction and pentacyclic framework installation. Notably, extracts from Aspidosperma subincanum showed strong antibacterial activity against Xanthomonas citri, while both HE-GL and HE-GS inhibited acetylcholinesterase. To date, no major safety concerns or drug interactions have been recorded for these compounds.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study achieved enantioselective total syntheses of bisleuconothine A and bousigonine B, revising their absolute stereochemistry.
- The study achieved a collective asymmetric synthesis of 11 aspidosperma indole alkaloids and a formal synthesis of (-)-deoxoapodine using a [3.3.1]-bicyclic ring system construction and a pentacyclic framework installation.
- The study achieved the enantioselective total syntheses of (-)-aspidospermidine and (+)-quebrachamine using chiral lithium amide alkylation.
- HE-GL from Aspidosperma subincanum showed strong antibacterial activity against Xanthomonas citri, while both HE-GL and HE-GS inhibited acetylcholinesterase.
Frequently asked questions
What is Aspidosperma?
Aspidosperma (Aspidosperma) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Aspidosperma?
4 sourced findings are recorded for Aspidosperma; the strongest carries evidence grade D. For example: The study achieved enantioselective total syntheses of bisleuconothine A and bousigonine B, revising their absolute stereochemistry.
How strong is the evidence for Aspidosperma?
The strongest finding for Aspidosperma carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Aspidosperma safe? What are the side effects?
No major safety issues are recorded for Aspidosperma in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Aspidosperma interact with medications?
No drug interactions are recorded for Aspidosperma in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Aspidosperma?
Aspidosperma is also known as: Аспидосперма.
Is Aspidosperma a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Divergent Enantioselective Total Synthesis of Aspidosperma Indole Alkaloids. literature abstract metadata
- T2 Enantioselective Total Syntheses of Bisleuconothine A and Bousigonine B. literature abstract metadata
- T2 Sesquiterpene-rich n-hexane extracts from Aspidosperma subincanum Mart.: anti-Xanthomonas citri activity, acetylcholinesterase inhibition and insights into molecular docking. literature abstract metadata
- T2 Enantioselective Synthesis of (-)-Aspidospermidine and (+)-Quebrachamine via Chiral Lithium Amide Alkylation of Alkynylacetic Acids. literature abstract metadata