Aspidosperma
Aspidosperma
Aspidosperma is a plant traditionally not associated with any specific medicinal uses in known historical or cultural practices. Scientific research has focused on its chemical composition, achieving enantioselective total syntheses of various alkaloids such as bisleuconothine A, bousigonine B, (-)-aspidospermidine, and (+)-quebrachamine. Additionally, studies have shown that hexane-ethyl acetate (HE-GL) fractions from Aspidosperma subincanum exhibit strong antibacterial activity against Xanthomonas citri, while both HE-GL and HE-glycerol (HE-GS) show moderate acetylcholinesterase inhibition. These findings suggest potential applications in antibacterial and neurochemical contexts but require further investigation to confirm their efficacy. No major safety concerns or reported drug interactions have been recorded for Aspidosperma, indicating that it may be used without significant risk when handled appropriately.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study achieved enantioselective total syntheses of bisleuconothine A and bousigonine B, revising their absolute stereochemistry.
- The study achieved a collective asymmetric synthesis of 11 aspidosperma indole alkaloids and a formal synthesis of (-)-deoxoapodine using a [3.3.1]-bicyclic ring system construction and a pentacyclic framework installation.
- The study achieved the enantioselective total syntheses of (-)-aspidospermidine and (+)-quebrachamine using chiral lithium amide alkylation.
- HE-GL from Aspidosperma subincanum showed strong antibacterial activity against Xanthomonas citri, while both HE-GL and HE-GS inhibited acetylcholinesterase.
Frequently asked questions
What is Aspidosperma?
Aspidosperma (Aspidosperma) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Aspidosperma?
4 sourced findings are recorded for Aspidosperma; the strongest carries evidence grade D. For example: The study achieved enantioselective total syntheses of bisleuconothine A and bousigonine B, revising their absolute stereochemistry.
How strong is the evidence for Aspidosperma?
The strongest finding for Aspidosperma carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Aspidosperma safe? What are the side effects?
No major safety issues are recorded for Aspidosperma in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Aspidosperma interact with medications?
No drug interactions are recorded for Aspidosperma in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Aspidosperma?
Aspidosperma is also known as: Аспидосперма.
Is Aspidosperma a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Divergent Enantioselective Total Synthesis of Aspidosperma Indole Alkaloids. literature abstract metadata
- T2 Enantioselective Total Syntheses of Bisleuconothine A and Bousigonine B. literature abstract metadata
- T2 Sesquiterpene-rich n-hexane extracts from Aspidosperma subincanum Mart.: anti-Xanthomonas citri activity, acetylcholinesterase inhibition and insights into molecular docking. literature abstract metadata
- T2 Enantioselective Synthesis of (-)-Aspidospermidine and (+)-Quebrachamine via Chiral Lithium Amide Alkylation of Alkynylacetic Acids. literature abstract metadata