Astragalus (plant)
Astragalus
黄芪是一种传统中药植物，具有根和根茎，用于各种草药配方。传统上，它因其对免疫功能的潜在益处以及治疗疲劳、感冒和呼吸系统问题等状况而被使用；然而，具体的用途可能因不同的传统而异，并且没有统一记录。 科学证据表明黄芪可能具有潜在的抗癌作用，特别是在与其他草药如Curcuma zedoaria结合使用时。此外，研究表明黄芪中的化合物，例如AmCHI，在外源性激素的影响下参与了黄酮类生物合成。在动物模型中，补充黄芪和发酵黄芪均显示出对吐鲁番黑绵羊乳汁分泌性能和抗氧化能力的改善，尽管两种治疗之间的效果并不相同。此外，含有黄芪的Qishen Yiqi 滴丸被发现通过靶向TGF-β/Periostin途径减轻了心肌缺血再灌注诱导的纤维化损伤。 基于当前数据的安全性问题很小；没有记录到严重的问题。也没有证据表明黄芪与药物之间存在显著的相互作用，尽管进一步的研究将有助于获得更全面的理解。
- 最佳证据
- A
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 研究发现，黄芪-莪术组合可以调节基因表达并靶向肺癌鳞状细胞的血管内皮细胞。
- 研究发现，来自蒙古黄芪的AmCHI在黄酮类生物合成中起关键作用，并受外源激素的影响。
- 同时补充黄芪和发酵黄芪可以改善吐鲁番黑羊的泌乳性能和抗氧化能力，尽管两种治疗方式的效果有所不同。
- 研究发现，含有黄芪的启 Shen 益气滴丸通过靶向TGF-β/骨连接蛋白途径减轻心肌缺血再灌注引起的纤维化损伤。
- 黄芪提取物在六分钟步行测试中（89.5%）显示出优于其他植物提取物的效果，用于评估心力衰竭患者的疗效，但结果基于有限的研究。
- 一项网络meta分析表明，将含有黄芪的传统中药口服制剂与西药治疗相结合可能改善心力衰竭管理的各个方面，但需要更多的研究。
- 研究发现，从黄芪中提取的异黄酮和 Salvianolic 酸 B 可通过下调 MBOAT2 和抑制 JAK/STAT 途径来抑制胰腺癌的发展。
- 这篇评论提出了一种三阶段策略，使用植物衍生化合物依次破坏、唤醒和杀死生物膜内的细菌持久菌。
Frequently asked questions
What is Astragalus (plant)?
Astragalus (plant) (Astragalus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Astragalus (plant)?
8 sourced findings are recorded for Astragalus (plant); the strongest carries evidence grade A. For example: 研究发现，黄芪-莪术组合可以调节基因表达并靶向肺癌鳞状细胞的血管内皮细胞。
How strong is the evidence for Astragalus (plant)?
The strongest finding for Astragalus (plant) carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Astragalus (plant) safe? What are the side effects?
No major safety issues are recorded for Astragalus (plant) in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Astragalus (plant) interact with medications?
No drug interactions are recorded for Astragalus (plant) in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Astragalus (plant)?
Astragalus (plant) is also known as: астрагал, Astragale.
Is Astragalus (plant) a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 The clinical efficacy of Astragalus-containing Chinese patent medicines in the effective treatment of heart failure: A systematic review and network meta-analysis. literature abstract metadata
- T2 The effects of supplementing Astragalus and fermented Astragalus on lactation performance, rumen microbiota, and lamb weight gain in Turpan black sheep. literature abstract metadata
- T2 Functional characterization of type I chalcone isomerase AmCHI from Astragalus mongholicus and its response mechanism to exogenous hormones. literature abstract metadata
- T2 Integrating Seropharmacology, Network Pharmacology, and Single-Cell Transcriptomics to Decipher the Dual Anti-Tumor Mechanisms of Astragalus-Curcuma zedoaria in Lung Squamous Cell Carcinoma. literature abstract metadata
- T2 Qishen Yiqi Dripping Pills Alleviate Myocardial Ischemia-Reperfusion-Induced Fibrotic Injury by Inhibiting Fibroblast Activation via the Transforming Growth Factor-Beta/Periostin Pathway. literature abstract metadata
- T2 Targeting pancreatic cancer progression: The formononetin and salvianolic acid B combination suppresses JAK/STAT signaling via MBOAT2 downregulation. literature abstract metadata
- T2 Sequential eradication of bacterial persisters: integrating phytochemical pharmacology with microenvironment-responsive delivery strategies. literature abstract metadata
- T2 Efficacy of plant extracts in heart failure patients: a systematic review and network meta-analysis. literature abstract metadata