FolkKB

Java brucea

Brucea javanica

布鲁斯嘉纳是一种传统植物，在亚洲医学中，特别是在中医实践中被广泛使用。它没有被传统地记录为特定用途的药物，但在现代科学研究中显示出前景。研究表明，其提取物可能通过针对CDK1、HOXC10和MTFR2抑制口腔鳞状细胞癌的发展，这表明在与常规化疗结合治疗癌症时可能存在潜在益处。此外，来自各种植物（包括布鲁斯嘉纳）的多氢黄酮类化合物（PDVLNs）正在探索作为抗癌药物递送系统，由于它们具有抗肿瘤特性。然而，这些成分的临床应用和配方仍在研究中，突显了其开发中的挑战。

速览
最佳证据
A
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 来自多种植物的 PDVLN，包括布鲁氏木豆，作为药物递送系统在癌症治疗中显示出潜力。 D PMID
  • 这项研究发现，AS/BJO-NEs通过下调CDK1、HOXC10和MTFR2抑制了口腔鳞状细胞癌。 D PMID
  • 研究发现，将传统中药与常规化疗联合使用可能提高晚期结直肠癌患者的疾病控制率、客观缓解率和生活质量。 A PMID
  • 研究发现，布鲁斯氏木豆含有超过100种具有通过多种信号途径的抗肿瘤活性的喹桑内酯，但在制剂和安全性方面面临挑战。 D PMID

Frequently asked questions

What is Java brucea?

Java brucea (Brucea javanica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Java brucea?

4 sourced findings are recorded for Java brucea; the strongest carries evidence grade A. For example: 来自多种植物的 PDVLN，包括布鲁氏木豆，作为药物递送系统在癌症治疗中显示出潜力。

How strong is the evidence for Java brucea?

The strongest finding for Java brucea carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Java brucea safe? What are the side effects?

No major safety issues are recorded for Java brucea in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Java brucea interact with medications?

No drug interactions are recorded for Java brucea in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Java brucea?

Java brucea is also known as: Бруцея яванская.

Is Java brucea a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Beneficial effects of proprietary Chinese medicines as adjuvant therapy in patients with advanced colorectal cancer: A meta-analysis. literature abstract metadata
  2. T2 The astragaloside-brucea javanica oil nanoemulsion inhibiting the progression of oral squamous cell carcinoma through CDK1- HOXC10-MTFR2 pathway. literature abstract metadata
  3. T2 Multi-dimensional insights into Brucea javanica (L.) Merr. in cancer treatment: current status, challenges and future directions. literature abstract metadata
  4. T2 Green nanomedicine for cancer therapy. literature abstract metadata