FolkKB

Java brucea

Brucea javanica

布鲁斯嘉纳是一种传统上在某些亚洲草药实践中使用的植物。虽然布鲁斯嘉纳的具体传统用途没有很好地记录，但它已被研究其潜在的抗肿瘤特性。科学证据表明，从布鲁斯嘉纳和其他植物中提取的脂质纳米颗粒（PDVLNs）作为癌症治疗中的药物递送系统具有前景，特别是通过下调特定蛋白质来抑制口腔鳞状细胞癌。研究表明，将传统中药与常规化疗结合使用可能增强晚期结直肠癌患者的癌症治疗方法的有效性。然而，尽管该植物含有超过100种具有不同信号途径的抗肿瘤活性的奎桑内酯，仍存在配方和安全性方面的挑战。迄今为止尚未记录到重大安全问题或药物相互作用。

速览
最佳证据
A
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 来自多种植物的 PDVLN，包括布鲁氏木豆，作为药物递送系统在癌症治疗中显示出潜力。 D PMID
  • 这项研究发现，AS/BJO-NEs通过下调CDK1、HOXC10和MTFR2抑制了口腔鳞状细胞癌。 D PMID
  • 研究发现，将传统中药与常规化疗联合使用可能提高晚期结直肠癌患者的疾病控制率、客观缓解率和生活质量。 A PMID
  • 研究发现，布鲁斯氏木豆含有超过100种具有通过多种信号途径的抗肿瘤活性的喹桑内酯，但在制剂和安全性方面面临挑战。 D PMID

Frequently asked questions

What is Java brucea?

Java brucea (Brucea javanica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Java brucea?

4 sourced findings are recorded for Java brucea; the strongest carries evidence grade A. For example: 来自多种植物的 PDVLN，包括布鲁氏木豆，作为药物递送系统在癌症治疗中显示出潜力。

How strong is the evidence for Java brucea?

The strongest finding for Java brucea carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Java brucea safe? What are the side effects?

No major safety issues are recorded for Java brucea in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Java brucea interact with medications?

No drug interactions are recorded for Java brucea in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Java brucea?

Java brucea is also known as: Бруцея яванская.

Is Java brucea a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Beneficial effects of proprietary Chinese medicines as adjuvant therapy in patients with advanced colorectal cancer: A meta-analysis. literature abstract metadata
  2. T2 The astragaloside-brucea javanica oil nanoemulsion inhibiting the progression of oral squamous cell carcinoma through CDK1- HOXC10-MTFR2 pathway. literature abstract metadata
  3. T2 Multi-dimensional insights into Brucea javanica (L.) Merr. in cancer treatment: current status, challenges and future directions. literature abstract metadata
  4. T2 Green nanomedicine for cancer therapy. literature abstract metadata