Chinese boxwood
Buxus sinica
Buxus sinica，又称中国冬青，是一种传统上在东亚医学中使用的植物。尽管其具体的传统用途尚未详细记录，但已对其进行了潜在治疗效果的研究。科学研究通过集成分子网络和衍生化技术发现了 Buxus sinica 中的56种生物碱。一种化合物 CVB-D 通过上调 SIRT3 增强了糖尿病性心肌病小鼠的心肌功能并减轻了心肌细胞衰老，SIRT3 能去乙酰化 ATP5O。此外，某些生物碱表现出对乙酰胆碱酯酶的抑制作用，并通过 miR-30b-5p/ALCAT1 途径保护心肌功能以缓解醛固酮诱导的心脏肥大。虽然尚未记录到重大安全问题或药物相互作用，但这些发现是初步的，需要进一步研究来确认这些潜在的好处。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 这项研究使用集成分子网络和衍生化技术对56种贝氏冬青中的生物碱进行了表征。
- CVB-D 治疗通过上调 SIRT3 和乙酰化 ATP5O 改善糖尿病心肌病小鼠的线粒体功能并减轻心肌细胞衰老。
- 研究从冬青属植物Buxus sinica中鉴定出了十五个新的去水苏碱类生物碱，其中一些显示出对乙酰胆碱酯酶的抑制作用。
- CVB-D通过miR-30b-5p/ALCAT1途径改善小鼠和细胞的心肌肥厚和线粒体功能。
Frequently asked questions
What is Chinese boxwood?
Chinese boxwood (Buxus sinica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Chinese boxwood?
4 sourced findings are recorded for Chinese boxwood; the strongest carries evidence grade D. For example: 这项研究使用集成分子网络和衍生化技术对56种贝氏冬青中的生物碱进行了表征。
How strong is the evidence for Chinese boxwood?
The strongest finding for Chinese boxwood carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Chinese boxwood safe? What are the side effects?
No major safety issues are recorded for Chinese boxwood in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Chinese boxwood interact with medications?
No drug interactions are recorded for Chinese boxwood in our sources. This does not rule them out — check with a pharmacist.
Is Chinese boxwood a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Cyclovirobuxine D ameliorates cardiomyocyte senescence in diabetic cardiomyopathy mice by enhancing mitochondrial function via sirtuin 3-ATP5O signal axis. literature abstract metadata
- T2 Cyclovirobuxine D ameliorates cardiac hypertrophy by enhancing mitochondrial function via miR-30b-5p/ALCAT1 Pathway. literature abstract metadata
- T2 Triterpene alkaloids from Buxus sinica and their anti-AChE activities. literature abstract metadata
- T2 Comprehensive profiling of alkaloids in Buxus sinica by integrating global natural products social molecular networking with derivatization-assisted characteristic ion filtering. literature abstract metadata