Chinese boxwood
Buxus sinica
Buxus sinica, commonly known as Chinese boxwood, is a traditional plant used in Asian medicine. While its specific uses within traditional practices are not well-documented, studies have identified 56 alkaloids in Buxus sinica through advanced molecular techniques. Research indicates that CVB-D treatment from this plant may improve mitochondrial function and alleviate cardiomyocyte senescence in diabetic cardiomyopathy mice by upregulating SIRT3 and acetylating ATP5O. Additionally, some newly identified alkaloids showed inhibitory effects on acetylcholinesterase. CVB-D also improves cardiac hypertrophy and mitochondrial function through the miR-30b-5p/ALCAT1 pathway in both mice and cells. To date, no major safety concerns or recorded drug interactions have been noted for Buxus sinica.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- This study characterized 56 alkaloids in Buxus sinica using integrated molecular networking and derivatization techniques.
- CVB-D treatment improves mitochondrial function and alleviates cardiomyocyte senescence in diabetic cardiomyopathy mice via upregulating SIRT3 and acetylating ATP5O.
- The study identified fifteen new Buxus alkaloids from Buxus sinica, some of which showed inhibitory effects on acetylcholinesterase.
- CVB-D improves cardiac hypertrophy and mitochondrial function in mice and cells through the miR-30b-5p/ALCAT1 pathway.
Frequently asked questions
What is Chinese boxwood?
Chinese boxwood (Buxus sinica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Chinese boxwood?
4 sourced findings are recorded for Chinese boxwood; the strongest carries evidence grade D. For example: This study characterized 56 alkaloids in Buxus sinica using integrated molecular networking and derivatization techniques.
How strong is the evidence for Chinese boxwood?
The strongest finding for Chinese boxwood carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Chinese boxwood safe? What are the side effects?
No major safety issues are recorded for Chinese boxwood in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Chinese boxwood interact with medications?
No drug interactions are recorded for Chinese boxwood in our sources. This does not rule them out — check with a pharmacist.
Is Chinese boxwood a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Cyclovirobuxine D ameliorates cardiomyocyte senescence in diabetic cardiomyopathy mice by enhancing mitochondrial function via sirtuin 3-ATP5O signal axis. literature abstract metadata
- T2 Cyclovirobuxine D ameliorates cardiac hypertrophy by enhancing mitochondrial function via miR-30b-5p/ALCAT1 Pathway. literature abstract metadata
- T2 Triterpene alkaloids from Buxus sinica and their anti-AChE activities. literature abstract metadata
- T2 Comprehensive profiling of alkaloids in Buxus sinica by integrating global natural products social molecular networking with derivatization-assisted characteristic ion filtering. literature abstract metadata