Callicarpa kwangtungensis
Callicarpa kwangtungensis
Callicarpa kwangtungensis 是一种在传统医学中尚未广泛使用的植物。科学研究表明，来自该植物的化合物 poliumoside 可能通过调节小胶质细胞极化并减少炎症来缓解神经功能缺陷，并降低缺血性卒中后老鼠脑梗死面积。此外，CK 的给药导致认知功能显著改善，并在 APP/PS1 老鼠模型中减少了淀粉样蛋白 β 和神经纤维缠结的形成。通过真菌生物转化鉴定出六种具有 23‑norursane 三萜骨架的新代谢产物，其中一种显示出潜在的血管保护活性。该植物未记录主要安全问题或药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 聚乙二醇醛苷减轻了小鼠缺血性中风后的神经功能缺陷并缩小了梗死体积，通过调节小胶质细胞极化和减少炎症反应。
- 研究确定了传统Callicarpa属植物在药用制剂中可能的替代来源。
- CK 的给药导致了认知功能的显著改善，并减少了APP/PS1小鼠中的淀粉样β蛋白和神经纤维缠结形成。
- 通过真菌生物转化，鉴定出六种新的具有23-去雄甾烷三萜骨架的代谢物，并且其中一种显示出潜在的血管保护活性。
Frequently asked questions
What is Callicarpa kwangtungensis?
Callicarpa kwangtungensis (Callicarpa kwangtungensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Callicarpa kwangtungensis?
4 sourced findings are recorded for Callicarpa kwangtungensis; the strongest carries evidence grade D. For example: 聚乙二醇醛苷减轻了小鼠缺血性中风后的神经功能缺陷并缩小了梗死体积，通过调节小胶质细胞极化和减少炎症反应。
How strong is the evidence for Callicarpa kwangtungensis?
The strongest finding for Callicarpa kwangtungensis carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Callicarpa kwangtungensis safe? What are the side effects?
No major safety issues are recorded for Callicarpa kwangtungensis in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Callicarpa kwangtungensis interact with medications?
No drug interactions are recorded for Callicarpa kwangtungensis in our sources. This does not rule them out — check with a pharmacist.
Is Callicarpa kwangtungensis a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Six undescribed 23-norursane triterpenoids from the biotransformation of ilexgenin a by endophytic fungi and their vascular protective activity. literature abstract metadata
- T2 Phytochemical analysis of different Callicarpa species based on integrating metabolomics and chemometrics. literature abstract metadata
- T2 Integrating network pharmacology and multi-omics to explore the mechanism of Callicarpa kwangtungensis Chun in ameliorating Alzheimer's disease pathology in APP/PS1 mice. literature abstract metadata
- T2 Poliumoside alleviates microglia-mediated inflammation and blood-brain barrier disruption via modulating the polarization of microglia after ischemic stroke in mice. literature abstract metadata