FolkKB

Bengal-currants

Carissa carandas

卡里萨·卡兰达斯（又称印度木瓜或马哈恩果实），源自印度及其他亚洲地区的传统医学实践。传统上，它并未广泛用于特定的医疗用途。然而，科学研究表明其可能具有健康益处。一项为期28天的亚急性喂养试验显示，卡里萨·卡兰达斯果粉和甲醇提取物显著提高了血红蛋白、红细胞计数和血小板计数，且未见毒性作用。从植物中鉴定出的瓦尔格拉特（Valgrate）显示出作为GGT抑制剂的潜力，在体外和分子对接研究中；然而，需要进一步临床研究来证实这些发现。此外，卡里萨·卡兰达斯中的乌索酸（UA）在体外对A549 NSCLC细胞表现出显著的抗癌活性，并具有多重作用机制。CeO2纳米颗粒通过调节小鼠TGF-β/Smads和Nrf2/HO-1信号通路减轻了肝纤维化，暗示潜在的治疗应用。迄今为止未发现重大安全问题或记录在案的药物相互作用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 28天的亚急性喂食试验使用Carissa carandas果粉和甲醇提取物，显示出血红蛋白、血细胞比容和血小板计数显著增加，而无毒理学影响。 D PMID
  • 研究发现，从卡拉灿树（Carissa carandas）中鉴定出的化合物瓦尔特雷（Valtrate）在体外和通过分子对接显示出作为GGT抑制剂的潜力，但需要进一步的临床调查。 D PMID
  • 来自Carissa carandas的UA在体外对A549 NSCLC细胞显示出显著的抗癌活性并具有多重作用。 D PMID
  • CeO2NPs通过调节大鼠的TGF-β/Smads和Nrf2/HO-1信号通路来缓解肝纤维化。 D PMID

Frequently asked questions

What is Bengal-currants?

Bengal-currants (Carissa carandas) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Bengal-currants?

4 sourced findings are recorded for Bengal-currants; the strongest carries evidence grade D. For example: 28天的亚急性喂食试验使用Carissa carandas果粉和甲醇提取物，显示出血红蛋白、血细胞比容和血小板计数显著增加，而无毒理学影响。

How strong is the evidence for Bengal-currants?

The strongest finding for Bengal-currants carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Bengal-currants safe? What are the side effects?

No major safety issues are recorded for Bengal-currants in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Bengal-currants interact with medications?

No drug interactions are recorded for Bengal-currants in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Bengal-currants?

Bengal-currants is also known as: Каранда, Prune de Damas.

Is Bengal-currants a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Cerium oxide nanoparticles attenuate hepatic failure via blocking TGF-β/Smads and upregulating Nrf2/HO-1 signaling pathways in liver fibrosis rat model. literature abstract metadata
  2. T2 Antioxidant activity and in-silico evaluation of natural compounds of Carissa carandas as potential inhibitors of Gamma-Glutamyl Transpeptidase to enhance the efficacy of chemotherapy drugs against prostate cancer. literature abstract metadata
  3. T2 Ursolic acid from Carissa carandas L. as a multi-target agent against NSCLC: An Integrative in silico and in vitro study. literature abstract metadata
  4. T2 Carissa carandas L. and Its Methanol Extracts Promote Hematopoiesis and Thrombocytopoiesis: A Sub-Acute Toxicological Study in Experimental Rats. literature abstract metadata