Lojabark
Cinchona officinalis
金鸡纳树（Cinchona officinalis），又称金鸡纳树或奎宁皮，起源于南美洲，并在土著医学中有悠久的传统。它传统上用于治疗疟疾，因为其奎宁含量被Quechua人认可，后来被纳入西方医学。科学研究表明，奎宁-查孔醇杂交体的衍生物表现出对EBC-1细胞的强大细胞毒性和抗增殖作用，而叶提取物显示出对抗多重耐药性假单胞菌（Pseudomonas aeruginosa）的一些抗生素活性；然而，这些发现是初步的，并需要进一步验证以用于临床应用。体外试验表明，家用金鸡纳树（CO）-MT可能通过89%抑制SARS-CoV-2感染，与瑞德西韦相当，但需要更多研究来确认这些结果。尚未记录金鸡纳树的重大安全问题或药物相互作用；然而，进一步的研究是必要的以全面了解其潜在的益处和风险。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- Cinchona officinalis leaf extract showed some improvement in antibiotic activity against multidrug-resistant Pseudomonas aeruginosa but required further investigation.
- 两种奎宁-香酮杂合物的衍生物在EBC-1细胞中表现出强大的细胞毒性和抗增殖作用。
- 奎宁表现出多种生物学活性，包括抗肿瘤、抗炎和减肥作用，但需要进一步研究以应用于临床。
- 体外试验表明，家用 Cinchona officinalis（CO）-MT 导致了对 VeroE6 细胞中 SARS-CoV-2 感染的 89% 抑制，类似于瑞德西韦。
- This study optimized two extraction methods, MAE and UAE, for quinine recovery from Cinchona officinalis bark, achieving high yields with improved efficiency compared to conventional techniques.
Frequently asked questions
What is Lojabark?
Lojabark (Cinchona officinalis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Lojabark?
5 sourced findings are recorded for Lojabark; the strongest carries evidence grade D. For example: Cinchona officinalis leaf extract showed some improvement in antibiotic activity against multidrug-resistant Pseudomonas aeruginosa but required further investigation.
How strong is the evidence for Lojabark?
The strongest finding for Lojabark carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Lojabark safe? What are the side effects?
No major safety issues are recorded for Lojabark in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Lojabark interact with medications?
No drug interactions are recorded for Lojabark in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Lojabark?
Lojabark is also known as: Quinquina officinalis.
Is Lojabark a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Antiviral Activity of Cinchona officinalis, a Homeopathic Medicine, against COVID-19. literature abstract metadata
- T2 Cinchonine: A Versatile Pharmacological Agent Derived from Natural Cinchona Alkaloids. literature abstract metadata
- T2 Phytochemical Composition, Antibacterial, and Antibiotic-Resistance Modulatory Activity of Extracts of Lippia multiflora Moldenke, Terminalia mollis M. A. Lawson, and Cinchona officinalis L. Against Multidrug-Resistant Pseudomonas aeruginos literature abstract metadata
- T2 Optimization of Two Methods for the Rapid and Effective Extraction of Quinine from Cinchona officinalis. literature abstract metadata
- T2 Quinine-chalcone hybrids as potent inhibitors of P-glycoprotein with apoptotic effects on EBC-1 cells. literature abstract metadata