Lojabark
Cinchona officinalis
金鸡纳树（Cinchona officinalis），又称金鸡纳树或秘鲁树皮，是一种传统的南美洲药用植物。其在民间医学中的应用历史悠久，在原住民和传统南美治疗实践中尤其用于治疗发热和疟疾。尽管其传统用途已得到充分记录，但支持这些用途的科学证据仍然有限。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 金鸡纳 officinalis 叶提取物在对抗多重耐药假单胞菌 aeruginosa 的抗生素活性方面显示出一些改善，但需要进一步研究。
- 两种奎宁-香酮杂合物的衍生物在EBC-1细胞中表现出强大的细胞毒性和抗增殖作用。
- 奎宁表现出多种生物学活性，包括抗肿瘤、抗炎和减肥作用，但需要进一步研究以应用于临床。
- 体外试验表明，家用 Cinchona officinalis（CO）-MT 导致了对 VeroE6 细胞中 SARS-CoV-2 感染的 89% 抑制，类似于瑞德西韦。
- 这项研究优化了两种提取方法（MAE 和 UAE），用于从金鸡纳树皮中回收奎宁，实现了与传统技术相比更高的产量和更高效的性能。
Frequently asked questions
What is Lojabark?
Lojabark (Cinchona officinalis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Lojabark?
5 sourced findings are recorded for Lojabark; the strongest carries evidence grade D. For example: 金鸡纳 officinalis 叶提取物在对抗多重耐药假单胞菌 aeruginosa 的抗生素活性方面显示出一些改善，但需要进一步研究。
How strong is the evidence for Lojabark?
The strongest finding for Lojabark carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Lojabark safe? What are the side effects?
No major safety issues are recorded for Lojabark in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Lojabark interact with medications?
No drug interactions are recorded for Lojabark in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Lojabark?
Lojabark is also known as: Quinquina officinalis.
Is Lojabark a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Antiviral Activity of Cinchona officinalis, a Homeopathic Medicine, against COVID-19. literature abstract metadata
- T2 Cinchonine: A Versatile Pharmacological Agent Derived from Natural Cinchona Alkaloids. literature abstract metadata
- T2 Phytochemical Composition, Antibacterial, and Antibiotic-Resistance Modulatory Activity of Extracts of Lippia multiflora Moldenke, Terminalia mollis M. A. Lawson, and Cinchona officinalis L. Against Multidrug-Resistant Pseudomonas aeruginos literature abstract metadata
- T2 Optimization of Two Methods for the Rapid and Effective Extraction of Quinine from Cinchona officinalis. literature abstract metadata
- T2 Quinine-chalcone hybrids as potent inhibitors of P-glycoprotein with apoptotic effects on EBC-1 cells. literature abstract metadata