Lojabark

Cinchona officinalis

Cinchona officinalis, commonly known as the cinchona tree or quinine bark, originates from South America and has a long-standing tradition in indigenous medicine. It is traditionally used for treating malaria due to its quinine content, which was historically recognized by the Quechua people before being adopted into Western medicine. Scientific evidence suggests that derivatives of quinine-chalcone hybrids exhibit potent cytotoxic and antiproliferative effects against EBC-1 cells, while leaf extracts show some improvement in antibiotic activity against multidrug-resistant Pseudomonas aeruginosa; however, these findings are preliminary and require further validation for clinical use. In vitro assays indicate that homeopathic Cinchona officinalis (CO)-MT may inhibit SARS-CoV-2 infection by 89%, comparable to remdesivir, though more research is needed to confirm these results. No significant safety concerns or drug interactions have been recorded for Cinchona officinalis; however, further studies are necessary to fully understand its potential benefits and risks.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • Cinchona officinalis leaf extract showed some improvement in antibiotic activity against multidrug-resistant Pseudomonas aeruginosa but required further investigation. D PMID
  • Two derivatives of quinine-chalcone hybrids showed potent cytotoxic and antiproliferative effects in EBC-1 cells. D PMID
  • Cinchonine exhibits multiple biological activities including anti-cancer, anti-inflammatory, and anti-obesity effects, but further research is needed for clinical applications. D PMID
  • In vitro assays showed that homeopathic Cinchona officinalis (CO)-MT caused 89% inhibition of SARS-CoV-2 infection in VeroE6 cells, similar to remdesivir. D PMID
  • This study optimized two extraction methods, MAE and UAE, for quinine recovery from Cinchona officinalis bark, achieving high yields with improved efficiency compared to conventional techniques. D PMID

Frequently asked questions

What is Lojabark?

Lojabark (Cinchona officinalis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Lojabark?

5 sourced findings are recorded for Lojabark; the strongest carries evidence grade D. For example: Cinchona officinalis leaf extract showed some improvement in antibiotic activity against multidrug-resistant Pseudomonas aeruginosa but required further investigation.

How strong is the evidence for Lojabark?

The strongest finding for Lojabark carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Lojabark safe? What are the side effects?

No major safety issues are recorded for Lojabark in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Lojabark interact with medications?

No drug interactions are recorded for Lojabark in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Lojabark?

Lojabark is also known as: Quinquina officinalis.

Is Lojabark a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Antiviral Activity of Cinchona officinalis, a Homeopathic Medicine, against COVID-19. literature abstract metadata
  2. T2 Cinchonine: A Versatile Pharmacological Agent Derived from Natural Cinchona Alkaloids. literature abstract metadata
  3. T2 Phytochemical Composition, Antibacterial, and Antibiotic-Resistance Modulatory Activity of Extracts of Lippia multiflora Moldenke, Terminalia mollis M. A. Lawson, and Cinchona officinalis L. Against Multidrug-Resistant Pseudomonas aeruginos literature abstract metadata
  4. T2 Optimization of Two Methods for the Rapid and Effective Extraction of Quinine from Cinchona officinalis. literature abstract metadata
  5. T2 Quinine-chalcone hybrids as potent inhibitors of P-glycoprotein with apoptotic effects on EBC-1 cells. literature abstract metadata