FolkKB

Lojabark

Cinchona officinalis

Cinchona officinalis is a flowering plant species central to various historical medicinal traditions. It has been traditionally employed as an astringent and to address conditions such as malaria, amebiasis, fever, dysentery, and various infections. Scientific evidence regarding its extracts is currently limited and requires further investigation. Some studies suggest leaf extracts may improve antibiotic activity against certain bacteria, while specific derivatives have shown cytotoxic effects in cell lines. Additionally, in vitro assays have indicated potential antiviral activity against SARS-CoV-2 in specific cell models. No major safety issues or notable drug interactions have been recorded in the available data.

At a glance
Traditionally for
astringent · infections
Traditions
traditional · TCM
Best evidence
D
Cautions
—

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

Traditional use

  • astringent traditional T3 DRDUKE
  • infections traditional T3 DRDUKE
  • malaria traditional T3 DRDUKE
  • amebiasis traditional T3 DRDUKE
  • anesthetic traditional T3 DRDUKE
  • bacterial infections traditional T3 DRDUKE
  • carditis traditional T3 DRDUKE
  • cold traditional T3 DRDUKE
  • dysentery traditional T3 DRDUKE
  • fever traditional T3 DRDUKE
  • flu traditional T3 DRDUKE
  • hangover TCM T3 DRDUKE
  • hemorrhoids traditional T3 DRDUKE
  • lumbago traditional T3 DRDUKE
  • neuralgia traditional T3 DRDUKE

What the science says

  • Cinchona officinalis leaf extract showed some improvement in antibiotic activity against multidrug-resistant Pseudomonas aeruginosa but required further investigation. D PMID
  • Two derivatives of quinine-chalcone hybrids showed potent cytotoxic and antiproliferative effects in EBC-1 cells. D PMID
  • Cinchonine exhibits multiple biological activities including anti-cancer, anti-inflammatory, and anti-obesity effects, but further research is needed for clinical applications. D PMID
  • In vitro assays showed that homeopathic Cinchona officinalis (CO)-MT caused 89% inhibition of SARS-CoV-2 infection in VeroE6 cells, similar to remdesivir. D PMID
  • This study optimized two extraction methods, MAE and UAE, for quinine recovery from Cinchona officinalis bark, achieving high yields with improved efficiency compared to conventional techniques. D PMID

Frequently asked questions

What is Lojabark?

Lojabark (Cinchona officinalis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What is Lojabark traditionally used for?

Traditional sources record Lojabark for: astringent, infections, malaria, amebiasis, anesthetic, bacterial infections. This reflects traditional use, not a proven medical treatment.

Which traditions use Lojabark?

Lojabark appears in these traditions in our sources: traditional, TCM.

What does the scientific evidence say about Lojabark?

5 sourced findings are recorded for Lojabark; the strongest carries evidence grade D. For example: Cinchona officinalis leaf extract showed some improvement in antibiotic activity against multidrug-resistant Pseudomonas aeruginosa but required further investigation.

How strong is the evidence for Lojabark?

The strongest finding for Lojabark carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Lojabark safe? What are the side effects?

No major safety issues are recorded for Lojabark in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Lojabark interact with medications?

No drug interactions are recorded for Lojabark in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Lojabark?

Lojabark is also known as: Quinquina officinalis.

Is Lojabark a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T3 Dr. Duke's Ethnobotanical Database public domain (USDA ARS — attribute Dr. Duke's)
  2. T2 Antiviral Activity of Cinchona officinalis, a Homeopathic Medicine, against COVID-19. literature abstract metadata
  3. T2 Cinchonine: A Versatile Pharmacological Agent Derived from Natural Cinchona Alkaloids. literature abstract metadata
  4. T2 Phytochemical Composition, Antibacterial, and Antibiotic-Resistance Modulatory Activity of Extracts of Lippia multiflora Moldenke, Terminalia mollis M. A. Lawson, and Cinchona officinalis L. Against Multidrug-Resistant Pseudomonas aeruginos literature abstract metadata
  5. T2 Optimization of Two Methods for the Rapid and Effective Extraction of Quinine from Cinchona officinalis. literature abstract metadata
  6. T2 Quinine-chalcone hybrids as potent inhibitors of P-glycoprotein with apoptotic effects on EBC-1 cells. literature abstract metadata

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