Colocynth

Citrullus colocynthis

Citrullus colocynthis, commonly known as bitter apple or bitter cucumber, is a plant native to the Mediterranean region and parts of Asia. Traditionally, its use has not been extensively documented in any specific medical traditions. Scientific evidence suggests that biosynthesized silver nanoparticles from Citrullus colocynthis leaves exhibit significant cytotoxic activity against certain cancer cell lines, indicating potential anti-cancer properties. Additionally, a study optimized hydroalcoholic extraction parameters for five African medicinal plants, including Citrullus colocynthis, which enhanced α-amylase inhibition and antioxidant activities. The plant has also been found to cause significant integument damage to the female tick H. dromedarii when immersed in 100 mg/mL of its ethanolic extract, suggesting potential use as a tick repellent or control agent. Three new species of Achromobacter were identified from Citrullus colocynthis and Peganum harmala, indicating the plant's role in expanding known bacterial diversity. No major safety issues have been recorded for this plant, nor are there any reported drug interactions at present.

速览
最佳证据
D
注意事项

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同,请查阅所引来源。

科学怎么说

  • 研究发现,从苦越瓜叶中生物合成的银纳米颗粒对某些癌细胞系显示出显著的细胞毒性活性。 D PMID
  • 研究优化了五种非洲药用植物的水醇提取参数,确定了增强α-淀粉酶抑制和抗氧化活性的条件。 D PMID
  • 研究发现,将雌性骆驼蜱Hyalomma dromedarii浸入黄瓜属苦瓜种的乙醇提取物中会导致显著的皮肤损伤。 D PMID
  • 从黄瓜属苦瓜和大麻籽属麻黄中鉴定出了三种新的Achromobacter菌种。 D PMID

Frequently asked questions

What is Colocynth?

Colocynth (Citrullus colocynthis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Colocynth?

4 sourced findings are recorded for Colocynth; the strongest carries evidence grade D. For example: 研究发现,从苦越瓜叶中生物合成的银纳米颗粒对某些癌细胞系显示出显著的细胞毒性活性。

How strong is the evidence for Colocynth?

The strongest finding for Colocynth carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Colocynth safe? What are the side effects?

No major safety issues are recorded for Colocynth in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Colocynth interact with medications?

No drug interactions are recorded for Colocynth in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Colocynth?

Colocynth is also known as: Колоцинт, Coloquinte.

Is Colocynth a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Optimizing Hydroalcoholic Extraction of African Medicinal Plants for Enhanced α-Amylase Inhibition and Functional Enrichment of Hypoglycemic Bread Doughs. literature abstract metadata
  2. T2 Histopathological effects of the fruit extract of Citrullus colocynthis on the integument of the female tick Hyalomma dromedarii. literature abstract metadata
  3. T2 Biological synthesis of silver nanoparticles using extracts from Citrullus colocynthis and their anticancer activity. literature abstract metadata
  4. T2 Genome-Resolved Delineation of Three Novel Endophytic Achromobacter Species from Desert Medicinal Plants. literature abstract metadata