Men-in-a-Boat
Colchicum
科克兰（Colchicum），特别是科克兰秋花，是一种传统上在民间医学中使用的植物，但缺乏对其具体传统用途的详细记录。科学研究表明，从科克兰和玫瑰果中提取的物质显示出可变的抗氧化、抗菌和抗生物膜活性，萃取方法显著影响生物活性。一项病例报告描述了由于意外摄入科克兰秋花而导致的轻度肾功能和肝功能损害，并在重症监护室成功治疗。另一项研究指出，在包含科克兰秋花、甘草根（Withania somnifera）和橄榄树皮（Pistacia lentiscus）的植物组合中使用时，膝关节骨关节炎症状有所改善，与安慰剂相比效果轻微。优化科克兰生物碱生产过程的研究也在进行中，4小时静置/15分钟浸渍方案显示出前景。迄今为止尚未记录重大安全问题或药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 4 小时等待/15 分钟浸泡方案优化了 Colchicum autumnale 和 Colchicum bivonae 的生长和秋水仙碱含量。
- 研究发现，仅开口的水力条件与底部刷块结合提供了对上游通过Chondrostoma colchicum和Squalius cappadocicus（尤其是较小尺寸类别）最包容的解决方案。
- 研究发现，秋水仙和山楂提取物显示出可变的抗氧化、抗菌和抗生物膜活性，萃取策略是生物活性的关键决定因素。
- 研究报道了一例由于误食Colchicum autumnale 导致的中度肾功能和肝功能损害，经过积极治疗后成功康复。
- 这项研究发现，包含Colchicum autumnale、Withania somnifera和Pistacia lentiscus的草药组合在膝关节骨关节炎症状方面与安慰剂相比显示出适度的改善。
- 这项研究未在测试的五种百合属植物中发现秋水仙碱或其生物合成前体，反驳了长期存在的误解。
- 在超过十年的时间里，英国报告了57例秋水仙碱中毒儿童病例，死亡剂量在0.21至1.45毫克/公斤之间。
Frequently asked questions
What is Men-in-a-Boat?
Men-in-a-Boat (Colchicum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Men-in-a-Boat?
7 sourced findings are recorded for Men-in-a-Boat; the strongest carries evidence grade D. For example: 4 小时等待/15 分钟浸泡方案优化了 Colchicum autumnale 和 Colchicum bivonae 的生长和秋水仙碱含量。
How strong is the evidence for Men-in-a-Boat?
The strongest finding for Men-in-a-Boat carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Men-in-a-Boat safe? What are the side effects?
No major safety issues are recorded for Men-in-a-Boat in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Men-in-a-Boat interact with medications?
No drug interactions are recorded for Men-in-a-Boat in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Men-in-a-Boat?
Men-in-a-Boat is also known as: Безвременник, colchique.
Is Men-in-a-Boat a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 The effect of a multi-herbal product, C. autumnale, W. somnifera, and P. lentiscus, on knee osteoarthritis: a triple-blind randomized clinical trial. literature abstract metadata
- T2 Paediatric colchicine poisoning in the UK: a 10-year retrospective case series from the National Poisons Information Service. literature abstract metadata
- T2 LC-MS-Based Screening for Colchicine and Characterization of Major Bitter Constituents in Lily. literature abstract metadata
- T2 Successful Management of Accidental Colchicine Intoxication After Ingestion of Colchicum autumnale: A Case Report. literature abstract metadata
- T2 Evaluation of Plant-Guided Strategies Against Clinical Multidrug-Resistant Pathogens: Preliminary Phytochemical Screening, Antioxidant Capacity, and Antibacterial/Antibiofilm Activity of Rosa canina and Colchicum autumnale Extracts. literature abstract metadata
- T2 Assessing Upstream Passage of Two Potamodromous Leuciscids in an Experimental Retrofitted Pool-Weir Fishway Physical Model. literature abstract metadata
- T2 Immersion Frequency Optimisation and Species-Specific Metabolic Profiles of Colchicum autumnale and Colchicum bivonae in Temporary Immersion Systems. literature abstract metadata