Asiatic dogwood
Cornus officinalis
山茱萸（Cornus officinalis）通常被称为狗皮树，是一种传统的中国草药，在各种草药疗法中被使用。尽管其具体的传统用途没有很好地记录下来，但它已被研究以了解其在不同领域的潜在健康益处。科学数据表明，从山茱萸中提取的玉米素可能为小鼠急性肝功能衰竭提供显著保护。此外，植物中的另一种化合物loganetin可以通过特定机制诱导AML细胞分化和染色体不稳定性，该机制涉及KLHL6介导的CDK2泛素化降解。此外，从山茱萸中提取的乙醇提取物在通过调节氧化应激、抑制凋亡并稳定帕拉奎特暴露斑马鱼中的多巴胺能/γ-氨基丁酸能神经传递方面显示出神经保护作用。这项研究还优化了使用深共熔溶剂进行提取的过程，以提高效率和生物活性。尚未发现山茱萸的重大安全问题或记录的药物相互作用，但进一步的研究是必要的，以全面了解其潜在的应用和效果。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 玉米黄素预处理在小鼠由LPS/D-甘氨酰胺诱导的急性肝衰竭中提供了显著的预防保护。
- 来自Cornus officinalis的loganetin通过KLHL6介导的CDK2泛素化降解诱导AML细胞分化和染色体不稳定性。
- 这项研究优化了超声辅助提取方法，使用深共晶溶剂从Cornus officinalis中提取多酚，显示出更高的效率和生物活性。
- 玉米属植物乙醇提取物通过调节氧化应激、抑制凋亡和稳定多巴胺能/γ-氨基丁酸能神经传导，在paraquat暴露的斑马鱼中显示出神经保护作用。
Frequently asked questions
What is Asiatic dogwood?
Asiatic dogwood (Cornus officinalis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Asiatic dogwood?
4 sourced findings are recorded for Asiatic dogwood; the strongest carries evidence grade D. For example: 玉米黄素预处理在小鼠由LPS/D-甘氨酰胺诱导的急性肝衰竭中提供了显著的预防保护。
How strong is the evidence for Asiatic dogwood?
The strongest finding for Asiatic dogwood carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Asiatic dogwood safe? What are the side effects?
No major safety issues are recorded for Asiatic dogwood in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Asiatic dogwood interact with medications?
No drug interactions are recorded for Asiatic dogwood in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Asiatic dogwood?
Asiatic dogwood is also known as: cornouiller officinal.
Is Asiatic dogwood a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 [Loganetin Induces AML Cell Differentiation and Chromosomal Instability via KLHL6-Mediated CDK2 Ubiquitination Degradation]. literature abstract metadata
- T2 Ultrasound-assisted deep eutectic solvent extraction of polyphenols from Cornus officinalis: Optimization, mechanisms, and bioactivity. literature abstract metadata
- T2 The Natural Compound Cornuside Protects Against Acute Liver Failure Induced by Lipopolysaccharide and D-Galactosamine. literature abstract metadata
- T2 Network-pharmacology-guided elucidation of Cornus officinalis-mediated protection against paraquat-induced neurotoxicity via restoration of dopaminergic and GABAergic signaling pathways. literature abstract metadata