Asiatic dogwood

Cornus officinalis, commonly known as dogwood, is a traditional Chinese medicinal plant used in various herbal remedies. While its specific traditional uses are not well-documented, it has been studied for its potential health benefits across different fields. Scientific evidence suggests that cornuside from Cornus officinalis may provide significant protection against acute liver failure in mice models. Additionally, loganetin, another compound found in the plant, can induce differentiation and chromosomal instability in AML cells through a specific mechanism involving KLHL6-mediated CDK2 ubiquitination degradation. Moreover, an ethanolic extract of Cornus officinalis has shown neuroprotective effects by modulating oxidative stress, inhibiting apoptosis, and stabilizing dopaminergic/GABAergic neurotransmission in paraquat-exposed zebrafish. This study also optimized the extraction process using deep eutectic solvents to improve efficiency and bioactivity. No major safety concerns or recorded drug interactions have been identified for Cornus officinalis, though further research is warranted to fully understand its potential applications and effects.

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.