Blackdot
Cullen corylifolium
Cullen corylifolium, also known as Australian tea tree or lemon ironwood, is a plant native to Australia. While it has been used in traditional medicine for various purposes, no specific traditional uses have been recorded. Scientific evidence suggests that the combined use of Cullen corylifolium with Reynoutria multiflora might exacerbate immune-mediated liver injury compared to using either herb alone. Additionally, four coumarins from P. corylifolia demonstrated varying cytotoxicity against certain cell lines in vitro. Compounds isolated from its seeds showed significant in vitro α-glucosidase inhibitory effects and induced apoptosis and autophagy in HepG2 cells through multiple signaling pathways. No major safety issues or drug interactions have been reported, but further research is needed to fully understand its potential benefits and risks.
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 来自Cullen corylifolium种子的三种异黄酮在体外显示出显著的α-葡萄糖苷酶抑制活性。
- P. corylifolia 中分离出的四种香豆素对A549和MDA-MB-231细胞表现出不同的细胞毒性。
- 与单独使用其中任何一种草本植物相比，同时使用 Reynoutria multiflora 和 Cullen corylifolium 治疗可能会加剧免疫介导的肝损伤。
- 从Cullen corylifolium中提取的bakuchiol在HepG2细胞中诱导了凋亡和细胞周期停滞。
Frequently asked questions
What is Blackdot?
Blackdot (Cullen corylifolium) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Blackdot?
4 sourced findings are recorded for Blackdot; the strongest carries evidence grade D. For example: 来自Cullen corylifolium种子的三种异黄酮在体外显示出显著的α-葡萄糖苷酶抑制活性。
How strong is the evidence for Blackdot?
The strongest finding for Blackdot carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Blackdot safe? What are the side effects?
No major safety issues are recorded for Blackdot in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Blackdot interact with medications?
No drug interactions are recorded for Blackdot in our sources. This does not rule them out — check with a pharmacist.
Is Blackdot a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Isolation, Cytotoxicity, and In-silico Screening of Coumarins from Psoralea corylifolia Linn. literature abstract metadata
- T2 Bakuchiol from Cullen corylifolium and its efficacy on apoptosis and autophagy in HepG2 cells. literature abstract metadata
- T2 Glycosidase inhibitory isoflavones from the seeds of Cullen corylifolium and their structure-activity relationship study. literature abstract metadata
- T2 A new incompatible combination: Reynoutria multiflora combined with Cullen corylifolium enhances idiosyncratic hepatotoxicity under immunological stress. literature abstract metadata