turmeric
Curcuma longa
姜黄（Curcuma longa），又称土茴香，是一种传统植物，在亚洲医学中根深蒂固，特别是在印度草医和中医实践中。传统上，它因其抗炎特性而被用于支持消化健康，尽管具体的使用记录在不同的传统之间差异很大。科学研究表明，姜黄素是姜黄中的活性成分，通过靶向TLR4表现出适度的抗炎作用，并显示出减少石墨烯氧化物复合材料功效的潜力，这表明其具有一定的抗菌益处。此外，研究表明姜黄素的代谢转化产生具有相似活性但活性降低的代谢产物，显示了在葡萄糖和脂质代谢、抗氧化状态、肠道健康、生产性能和肝保护方面的前景，在选定的实验模型中。安全记录良好，没有报告重大问题，并且与姜黄根使用相关的药物相互作用尚未记录。
- 最佳证据
- A
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 研究从姜黄（Curcuma longa）中鉴定出了十九种倍半萜，其中一种通过靶向TLR4表现出适度的抗炎活性。
- 研究发现，纳米姜黄素与石墨烯氧化物复合物（NC-rGO）的抗菌效果略优于姜黄素还原石墨烯（C-rGO）。
- 姜黄素的代谢转化产生如二氢姜黄素、四氢姜黄素和六氢姜黄素等减少的代谢物，这些代谢物在葡萄糖和脂质代谢中表现出与母体化合物相当的活性。
- 现有证据表明，在选择性的实验模型中抗氧化状态、肠道健康、生产性能和肝脏保护等方面表现出有希望的效果。
- 网络药理学分析表明，姜黄素可能通过靶向AURKA、BRAF（V600E）和CHEK1在TNBC中发挥抗肿瘤作用。
- 局部递送的姜黄素/姜提取物制剂与SRP联合使用可能会提供适度的PPD减少改善，但结果由于异质性和方法学限制而谨慎解释。
- 该研究提供了关于姜黄素在NF-κB p50的DNA识别区域附近潜在结合的计算证据，特征为减少的波动和有利的自由能贡献。
- 双去甲氧基姜黄素诱导自噬，降低了衰老标志物并减少了3xTg-AD小鼠海马区的Aβ负荷。
- 姜黄素增强超氧化物歧化酶活性，可能减轻心血管疾病中的氧化损伤。
Frequently asked questions
What is turmeric?
turmeric (Curcuma longa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about turmeric?
9 sourced findings are recorded for turmeric; the strongest carries evidence grade A. For example: 研究从姜黄（Curcuma longa）中鉴定出了十九种倍半萜，其中一种通过靶向TLR4表现出适度的抗炎活性。
How strong is the evidence for turmeric?
The strongest finding for turmeric carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is turmeric safe? What are the side effects?
No major safety issues are recorded for turmeric in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does turmeric interact with medications?
No drug interactions are recorded for turmeric in our sources. This does not rule them out — check with a pharmacist.
What are the common names of turmeric?
turmeric is also known as: куркума, Curcuma.
Is turmeric a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Investigation of Bioinspired Nanocurcumin Composites for Antibacterial Applications. literature abstract metadata
- T2 Structurally diverse sesquiterpenoids from Curcuma longa and their anti-inflammatory activities. literature abstract metadata
- T2 Superoxide Dismutase-Centered Modulation by Curcumin in Cardiovascular Diseases: Mechanistic Insights and Translational Implications. literature abstract metadata
- T2 Local curcumin/turmeric-derived delivery adjunctive to scaling and root planing for periodontitis: a systematic review and meta-analysis. literature abstract metadata
- T2 AMPK-mediated autophagy induction by bisdemethoxycurcumin attenuates senescence and amyloid pathology in 3xTg-AD mice. literature abstract metadata
- T2 Molecular dynamics and free energy analysis of curcumin binding near the DNA-recognition interface of NF-κB. literature abstract metadata
- T2 Curcuma longa L. and Curcumin in Veterinary Medicine and Animal Production: Phytochemistry, Biological Mechanisms and Practical Applications. literature abstract metadata
- T2 Curcumin Metabolites and Metabolic Health: Insights into Regulatory Mechanisms of Glucose and Lipid Homeostasis. literature abstract metadata
- T2 Integrated network pharmacology reveal new key curcumin-binding targets in triple-negative breast cancer. literature abstract metadata