Curcuma zanthorrhiza
Curcuma zanthorrhiza
姜黄素扎诺罗希亚是一种传统植物，在东南亚医学中被使用。尽管其具体用途尚未详细记录，但它作为小艾解毒汤（Xiao-Ai Jie-Du）的一部分被包括在内，该药剂传统上用于治疗某些健康状况。科学证据表明，它可能通过SIRT1激活和NFκB抑制机制对2型糖尿病产生潜在益处，尽管这些发现尚处于初步阶段。体外研究表明，(R)-(-)-姜黄素扎诺罗希醇可以抑制乳腺癌细胞的迁移和侵袭。此外，姜黄素扎诺罗希亚多酚提取物在大鼠中显示出显著降低肝酶水平和CYP450表达，暗示可能具有保护肝脏的作用。迄今为止，尚未记录该植物的重大安全问题或已知药物相互作用，但需要进一步研究以全面确认这些发现。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 研究发现姜黄素和番红花醇可能是SIRT1激活剂和NFκB抑制剂，这表明它们可能在对抗2型糖尿病方面具有潜在的用途。
- (R)-(-)-番泻醇以浓度依赖性方式显著抑制了MDA-MB-231细胞的迁移和侵袭，通过NF-κB信号通路抑制基质金属蛋白酶。
- 研究确定了姜黄素泽金花作为小艾解毒汤核心配方的一部分，该配方显示出对DLBCL细胞增殖的潜在抑制作用和诱导凋亡的作用。
- 最高剂量的多植物提取物显著降低了小鼠肝酶水平和CYP450表达。
Frequently asked questions
What is Curcuma zanthorrhiza?
Curcuma zanthorrhiza (Curcuma zanthorrhiza) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Curcuma zanthorrhiza?
4 sourced findings are recorded for Curcuma zanthorrhiza; the strongest carries evidence grade D. For example: 研究发现姜黄素和番红花醇可能是SIRT1激活剂和NFκB抑制剂，这表明它们可能在对抗2型糖尿病方面具有潜在的用途。
How strong is the evidence for Curcuma zanthorrhiza?
The strongest finding for Curcuma zanthorrhiza carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Curcuma zanthorrhiza safe? What are the side effects?
No major safety issues are recorded for Curcuma zanthorrhiza in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Curcuma zanthorrhiza interact with medications?
No drug interactions are recorded for Curcuma zanthorrhiza in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Curcuma zanthorrhiza?
Curcuma zanthorrhiza is also known as: Temu lawak.
Is Curcuma zanthorrhiza a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Computational evaluation of bioactive compounds in Curcuma zanthorrhiza targeting SIRT1 and NFκB. literature abstract metadata
- T2 Determination and mechanism of Xiao-Ai Jie-Du decoction against diffuse large B-cell lymphoma: In silico and In vitro studies. literature abstract metadata
- T2 (R)-(-)-Xanthorrhizol Inhibits the Migration and Invasion of Triple-Negative Breast Cancer Cells by Suppressing Matrix Metalloproteinases via the NF-κB Signaling Pathway. literature abstract metadata
- T2 Mitigating Tuberculosis Drug-induced Liver Injury: The Role of Moringa oleifera and Other Herbal Extracts. literature abstract metadata