Datura
Datura metel
杜尔他·梅特尔，也称为吉姆森草或印度吉姆森草，是一种在阿育吠陀和民间医学中传统使用的植物。它的主要用途是其精神活性作用，尽管没有记录特定的传统用途。科学证据表明，杜尔他·梅特尔与酒精的联合摄入可能对实验性大鼠的肝脏和前额叶皮层产生负面影响，这表明可能存在肝毒性效应。计算机分析表明，杜尔他·梅特尔中的四种植物化学物质可能是有效的EGFR抑制剂对抗肺癌，尽管需要进一步研究来验证这些发现。Bacillus velezensis DM中的一种糖甘油脂化合物显示出剂量依赖性的黑色素减少作用，但并未显著保护免受UVB诱导的损伤或表现出抗过敏活性。杜尔他·梅特尔生物碱的化学信息学分析确定了10种潜在的类似药物化合物具有药理性质，可能暗示潜在的治疗应用，尽管这些发现是初步的，需要进一步研究。没有记录到杜尔他·梅特尔的主要安全问题，但由于其精神活性特性，应谨慎使用。尚未报告有关该植物与其他药物相互作用的情况，但考虑到它对中枢神经系统的影响，对于特定健康状况的人或正在服用影响此系统的药物的人应谨慎考虑。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 将马兜铃与酒精联合摄入对实验大鼠的肝脏和前额叶皮层产生了负面影响。
- 该研究鉴定出枯草芽孢杆菌DM中的一种糖脂化合物，在剂量依赖性方面显示出减少黑色素水平的作用，但并未显著保护免受UVB诱导的损伤或表现出抗过敏活性。
- 化学信息学分析鉴定出10种具有托品烷类特征的潜在药用生物碱来自Datura metel。
- 该研究根据计算分析确定了从大头菜中分离出的四种植物化学物质可能作为针对肺癌的EGFR抑制剂。
Frequently asked questions
What is Datura?
Datura (Datura metel) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Datura?
4 sourced findings are recorded for Datura; the strongest carries evidence grade D. For example: 将马兜铃与酒精联合摄入对实验大鼠的肝脏和前额叶皮层产生了负面影响。
How strong is the evidence for Datura?
The strongest finding for Datura carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Datura safe? What are the side effects?
No major safety issues are recorded for Datura in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Datura interact with medications?
No drug interactions are recorded for Datura in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Datura?
Datura is also known as: Дурман индийский, Datura métel, Métel.
Is Datura a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Identification of Datura metel phytochemicals as potential EGFR inhibitors in lung cancer. literature abstract metadata
- T2 Chemoinformatic analysis of alkaloids of Datura metel and Datura stramonium species: insights from chemical space and diversity analysis. literature abstract metadata
- T2 Metabolite profiling of Bacillus velezensis DM extract linked to the rhizosphere of Datura metel L. and dermatoprotective potential of an isolated glycoglycerolipid. literature abstract metadata
- T2 Datura metel and Alcohol Cocktail Potentiates Hepatic Encephalopathy by Exacerbating Impairment via the Hepato-Prefrontal Cortical Axis. literature abstract metadata