Matchbox Bean
Entada phaseoloides
Entada phaseoloides，这种传统上未被广泛记录用于药用的植物，因其潜在的抗炎和免疫调节特性而受到科学界关注。研究表明，该植物提取物可能靶向ASCC2，以降低趋化因子表达并抑制NF‑κB激活，从而缓解与过敏接触性皮炎（ACD）相关的症状。此外，Entada phaseoloides在治疗银屑样皮炎方面显示出前景，通过恢复角质细胞稳态和抑制中性粒细胞胞外陷阱形成。 在痛风模型中，该植物提取物PHA显著抑制了NLRP3炎症小体的激活，并在体内外均减弱了炎症级联反应，提示其有望用于管理痛风症状。已鉴定并功能性表征四个UGT73家族基因，突出了它们在植物内黄酮和三萜糖苷化中的作用。值得注意的是，到目前为止尚未发现主要安全问题或记录的药物相互作用，表明该提取物具有总体安全性。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- EA 目标是 ASCC2，以减少趋化因子的表达并抑制 NF-κB 激活，从而缓解ACD症状。
- EA治疗显著缓解了由IMQ诱导的类牛皮癣性皮肤炎，通过恢复角质形成细胞稳态并抑制中性粒细胞胞外陷阱的形成。
- 在Entada phaseoloides中鉴定了四个UGT73家族基因并对其功能进行了表征，揭示了它们在黄酮和三萜糖基化中的作用。
- PHA 显著抑制了 NLRP3 炎症小体的激活，并在体内和体外痛风模型中减弱了炎症级联反应。
Frequently asked questions
What is Matchbox Bean?
Matchbox Bean (Entada phaseoloides) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Matchbox Bean?
4 sourced findings are recorded for Matchbox Bean; the strongest carries evidence grade D. For example: EA 目标是 ASCC2，以减少趋化因子的表达并抑制 NF-κB 激活，从而缓解ACD症状。
How strong is the evidence for Matchbox Bean?
The strongest finding for Matchbox Bean carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Matchbox Bean safe? What are the side effects?
No major safety issues are recorded for Matchbox Bean in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Matchbox Bean interact with medications?
No drug interactions are recorded for Matchbox Bean in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Matchbox Bean?
Matchbox Bean is also known as: Haricotier géant.
Is Matchbox Bean a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Phaseoloidin, a homogentisic acid glucoside from Entada phaseoloides, suppresses gout inflammation via NLRP3 inflammasome. literature abstract metadata
- T2 Exploring the substrate promiscuity and functional residues of UGT73 family enzymes in Entada phaseoloides. literature abstract metadata
- T2 Entadamide A-β-D-glucopyranoside attenuates psoriatic dermatitis by restoring keratinocyte homeostasis and suppressing neutrophil extracellular traps. literature abstract metadata
- T2 Entagenic acid targets ASCC2 to ameliorate allergic contact dermatitis via repressing NF‑κB transactivation and chemokine expression. literature abstract metadata