Matchbox Bean
Entada phaseoloides
Entada phaseoloides，一种传统上未记录用于医疗用途的植物，在科学研究中显示出前景。研究表明，它可能具有抗炎和免疫调节作用，通过靶向ACSC2减少趋化因子表达并抑制NF-κB激活来实现，这可以缓解与特应性皮炎（AD）相关的症状。此外，Entada phaseoloides治疗显著减轻了由咪喹莫特诱导的银屑病样皮炎，通过恢复角质形成细胞稳态和抑制中性粒细胞胞外陷阱形成。该植物在痛风管理方面也显示出潜力，通过抑制NLRP3炎症小体激活和减少炎症级联反应，在体内和体外模型中均有所体现。已鉴定并功能表征了四个UGT73家族基因，突显了它们在黄酮类和三萜糖苷化中的作用。值得注意的是，对该植物尚未记录主要的安全问题或已知的药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- EA 目标是 ASCC2，以减少趋化因子的表达并抑制 NF-κB 激活，从而缓解ACD症状。
- EA治疗显著缓解了由IMQ诱导的类牛皮癣性皮肤炎，通过恢复角质形成细胞稳态并抑制中性粒细胞胞外陷阱的形成。
- 在Entada phaseoloides中鉴定了四个UGT73家族基因并对其功能进行了表征，揭示了它们在黄酮和三萜糖基化中的作用。
- PHA 显著抑制了 NLRP3 炎症小体的激活，并在体内和体外痛风模型中减弱了炎症级联反应。
Frequently asked questions
What is Matchbox Bean?
Matchbox Bean (Entada phaseoloides) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Matchbox Bean?
4 sourced findings are recorded for Matchbox Bean; the strongest carries evidence grade D. For example: EA 目标是 ASCC2，以减少趋化因子的表达并抑制 NF-κB 激活，从而缓解ACD症状。
How strong is the evidence for Matchbox Bean?
The strongest finding for Matchbox Bean carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Matchbox Bean safe? What are the side effects?
No major safety issues are recorded for Matchbox Bean in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Matchbox Bean interact with medications?
No drug interactions are recorded for Matchbox Bean in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Matchbox Bean?
Matchbox Bean is also known as: Haricotier géant.
Is Matchbox Bean a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Phaseoloidin, a homogentisic acid glucoside from Entada phaseoloides, suppresses gout inflammation via NLRP3 inflammasome. literature abstract metadata
- T2 Exploring the substrate promiscuity and functional residues of UGT73 family enzymes in Entada phaseoloides. literature abstract metadata
- T2 Entadamide A-β-D-glucopyranoside attenuates psoriatic dermatitis by restoring keratinocyte homeostasis and suppressing neutrophil extracellular traps. literature abstract metadata
- T2 Entagenic acid targets ASCC2 to ameliorate allergic contact dermatitis via repressing NF‑κB transactivation and chemokine expression. literature abstract metadata