Matchbox Bean
Entada phaseoloides
Entada phaseoloides is a climbing plant often referred to as watervine. In various traditional practices, it is applied to address abdominal complaints, inflammation, malaria, sores, swelling, wounds, and intestinal issues such as enterosis or hematochezia. Some traditions also utilize it as an emetic or vermifuge. Scientific studies suggest that certain extracts may alleviate symptoms of acute colitis by targeting ASCC2 and inhibiting NF-kB activation. Research also indicates potential for managing psoriasiform dermatitis and suppressing NLRP3 inflammasome activation in gout models. No major safety issues or notable drug interactions are currently recorded in the available data.
- Traditionally for
- abdominal complaints · emetic
- Traditions
- traditional · Ayurveda
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
Traditional use
- abdominal complaints
- emetic
- enterosis
- hematochezia
- inflammation
- malaria
- sores
- swelling
- vermifuge
- water
- watervine
- wounds
What the science says
- EA targets ASCC2 to reduce chemokine expression and inhibit NF-κB activation, alleviating ACD symptoms.
- EA treatment significantly alleviated IMQ-induced psoriasiform dermatitis by restoring keratinocyte homeostasis and suppressing neutrophil extracellular trap formation.
- Four UGT73 family genes were identified and functionally characterized in Entada phaseoloides, revealing their roles in flavonoid and triterpenoid glycosylation.
- PHA significantly suppressed NLRP3 inflammasome activation and attenuated inflammatory cascades in both in vivo and in vitro gout models.
Frequently asked questions
What is Matchbox Bean?
Matchbox Bean (Entada phaseoloides) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What is Matchbox Bean traditionally used for?
Traditional sources record Matchbox Bean for: abdominal complaints, emetic, enterosis, hematochezia, inflammation, malaria. This reflects traditional use, not a proven medical treatment.
Which traditions use Matchbox Bean?
Matchbox Bean appears in these traditions in our sources: traditional, Ayurveda.
What does the scientific evidence say about Matchbox Bean?
4 sourced findings are recorded for Matchbox Bean; the strongest carries evidence grade D. For example: EA targets ASCC2 to reduce chemokine expression and inhibit NF-κB activation, alleviating ACD symptoms.
How strong is the evidence for Matchbox Bean?
The strongest finding for Matchbox Bean carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Matchbox Bean safe? What are the side effects?
No major safety issues are recorded for Matchbox Bean in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Matchbox Bean interact with medications?
No drug interactions are recorded for Matchbox Bean in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Matchbox Bean?
Matchbox Bean is also known as: Haricotier géant.
Is Matchbox Bean a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T3 Dr. Duke's Ethnobotanical Database public domain (USDA ARS — attribute Dr. Duke's)
- T2 Phaseoloidin, a homogentisic acid glucoside from Entada phaseoloides, suppresses gout inflammation via NLRP3 inflammasome. literature abstract metadata
- T2 Exploring the substrate promiscuity and functional residues of UGT73 family enzymes in Entada phaseoloides. literature abstract metadata
- T2 Entadamide A-β-D-glucopyranoside attenuates psoriatic dermatitis by restoring keratinocyte homeostasis and suppressing neutrophil extracellular traps. literature abstract metadata
- T2 Entagenic acid targets ASCC2 to ameliorate allergic contact dermatitis via repressing NF‑κB transactivation and chemokine expression. literature abstract metadata