Erythroxylum cuneatum
Erythroxylum cuneatum
Erythroxylum cuneatum，一种原产于中美洲的植物，在传统上没有用于任何特定的医疗用途。科学研究表明，其生物碱提取物可能表现出与美沙酮相似的特性，通过上调慢性吗啡引起的蛋白质表达并减少由吗啡诱导的神经母细胞瘤细胞中的细胞适应性来发挥作用。此外，在体外和大鼠模型中，Erythroxylum cuneatum的叶提取物显示出抗氧化和抗炎活性。体外研究还显示了细胞毒性作用，但在人类HepG2和WRL68细胞中没有显著的遗传毒性。目前尚未发现主要的安全问题或记录到的药物相互作用，但进一步的研究是必要的以充分了解其潜在的应用和效果。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 从楔叶相思木Erythroxylum cuneatum中提取的生物碱上调了由慢性吗啡引起的蛋白质表达，类似于美沙酮的作用。
- Erythroxylum cuneatum 吲哚碱叶提取物在体外和大鼠模型中显示出抗氧化和抗炎活性。
- Erythroxylum cuneatum 减少了神经母细胞瘤细胞对吗啡诱导的细胞适应性，类似于美沙酮的作用。
- Erythroxylum cuneatum 提取物显示出细胞毒性但对人类HepG2和WRL68细胞没有显著的遗传毒性。
Frequently asked questions
What is Erythroxylum cuneatum?
Erythroxylum cuneatum (Erythroxylum cuneatum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Erythroxylum cuneatum?
4 sourced findings are recorded for Erythroxylum cuneatum; the strongest carries evidence grade D. For example: 从楔叶相思木Erythroxylum cuneatum中提取的生物碱上调了由慢性吗啡引起的蛋白质表达，类似于美沙酮的作用。
How strong is the evidence for Erythroxylum cuneatum?
The strongest finding for Erythroxylum cuneatum carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Erythroxylum cuneatum safe? What are the side effects?
No major safety issues are recorded for Erythroxylum cuneatum in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Erythroxylum cuneatum interact with medications?
No drug interactions are recorded for Erythroxylum cuneatum in our sources. This does not rule them out — check with a pharmacist.
Is Erythroxylum cuneatum a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Assessment of genotoxicity and cytotoxicity of standardized aqueous extract from leaves of Erythroxylum cuneatum in human HepG2 and WRL68 cells line. literature abstract metadata
- T2 Morphine Antidependence of Erythroxylum cuneatum (Miq.) Kurz in Neurotransmission Processes In Vitro. literature abstract metadata
- T2 Antioxidant and anti-inflammatory properties of Erythroxylum cuneatum alkaloid leaf extract. literature abstract metadata
- T2 Erythroxylum cuneatum Prevented Cellular Adaptation in Morphineinduced Neuroblastoma Cells. literature abstract metadata