Gentiana lutea
Gentiana lutea
黄根（Gentiana lutea），又称黄根，是一种传统药草，原产于欧洲和亚洲。传统上，其使用在特定的医学实践中没有广泛记录；然而，在民间疗法中，它被用于消化问题和肝脏支持等多种用途。科学研究表明，黄根根提取物可能通过抗氧化和DNA修复机制对抗羟基脲诱导的DNA损伤具有保护作用。此外，研究表明，用GRE（黄根根提取物）预处理可以提高细胞活力并减少辐射细胞中的氧化性和基因组损伤。Gentiana lutea 和 Gentianella crispata 都在小鼠模型中显示出部分抗关节炎功效，但 G. crispata 更具前景。在支气管上皮细胞中，黄根根提取物的水溶液被发现可以保持上皮完整性并减少LPS诱导的IL-6和IL-8分泌而不会表现出细胞毒性。迄今为止，尚未记录到这种植物的重大安全问题或药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- GRE预处理显著改善了照射细胞的存活率并减少了氧化和基因损伤。
- 黄根和皱叶龙胆在大鼠模型中均显示出部分抗关节炎活性，其中皱叶龙胆更为有前景。
- 黄根提取物在人类外周血单核细胞中通过抗氧化和DNA修复机制对抗羟基脲诱导的DNA损伤显示出基因保护作用。
- 一种黄连根的水提取物未显示细胞毒性，保持了上皮完整性和减少了由LPS诱导的气道上皮细胞中IL-6和IL-8的分泌。
Frequently asked questions
What is Gentiana lutea?
Gentiana lutea (Gentiana lutea) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Gentiana lutea?
4 sourced findings are recorded for Gentiana lutea; the strongest carries evidence grade D. For example: GRE预处理显著改善了照射细胞的存活率并减少了氧化和基因损伤。
How strong is the evidence for Gentiana lutea?
The strongest finding for Gentiana lutea carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Gentiana lutea safe? What are the side effects?
No major safety issues are recorded for Gentiana lutea in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Gentiana lutea interact with medications?
No drug interactions are recorded for Gentiana lutea in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Gentiana lutea?
Gentiana lutea is also known as: Горечавка жёлтая, Gentiane jaune.
Is Gentiana lutea a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Gentiana lutea root aqueous extract mitigates hydroxyurea-induced genotoxicity through antioxidative action and DNA repair: an in vitro study in healthy human peripheral blood mononuclear cells. literature abstract metadata
- T2 Safety and anti-inflammatory activity of Gentiana lutea L. in human bronchial epithelial cell cultures. literature abstract metadata
- T2 Anti-inflammatory and pain-relieving effects of Gentiana lutea leaf and Gentianella crispata aerial part extracts in adjuvant-induced arthritis in rats. literature abstract metadata
- T2 Gentiana lutea Root Extract Attenuates Radiation-Induced Damage in Human PBMCs in vitro. literature abstract metadata