Japanese gentian
Gentiana scabra
Gentiana scabra 是一种传统中药，主要用于其声称的药理作用。虽然具体的传统用途没有详细记录，但它在东亚的各种医疗实践中被广泛使用。科学研究表明，Gentiana scabra 的疗效因环境而异；不同环境下生长的植物表现出不同的代谢差异和基因表达变化。研究表明，从 Gentiana scabra 提取的 GPS 治疗可以调节免疫稳态并抑制 NF-κB 激活来缓解类似银屑病的皮肤病变，并且在慢性应激性高血压大鼠中通过多种信号通路显示出降低血压的潜力。此外，植物提取物还显示出了对 Eimeria tenella 引起的鸡艾美耳球虫病的不同有效性，在 2 g/kg 的剂量下观察到最佳结果。安全性问题较小，因为迄今为止没有记录到重大问题或药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 在野生灌木丛、野生草地和耕作农田中生长的龙胆草（Gentiana scabra）中，发现了代谢差异和基因表达变化。
- GPS治疗显著减轻了小鼠类似牛皮癣的皮肤病变，通过调节免疫稳态和抑制NF-κB激活。
- 研究发现，龙胆泻肝丸可能通过多种信号途径降低慢性应激性高血压大鼠的血压。
- 甘草蔓荆子提取物在肉鸡因艾美耳球虫（Eimeria tenella）引起的球虫病中表现出不同的疗效，最佳效果为每千克体重2克。
Frequently asked questions
What is Japanese gentian?
Japanese gentian (Gentiana scabra) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Japanese gentian?
4 sourced findings are recorded for Japanese gentian; the strongest carries evidence grade D. For example: 在野生灌木丛、野生草地和耕作农田中生长的龙胆草（Gentiana scabra）中，发现了代谢差异和基因表达变化。
How strong is the evidence for Japanese gentian?
The strongest finding for Japanese gentian carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Japanese gentian safe? What are the side effects?
No major safety issues are recorded for Japanese gentian in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Japanese gentian interact with medications?
No drug interactions are recorded for Japanese gentian in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Japanese gentian?
Japanese gentian is also known as: Горечавка шероховатая, Gentiane japonaise.
Is Japanese gentian a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Gentiana scabra mitigates Eimeria tenella-induced Coccidiosis by regulating the gut microbiota-metabolome and strengthening the intestinal barrier. literature abstract metadata
- T2 The mechanism of Longdan Xiegan pills in chronic stress-induced hypertension:a study based on network pharmacology and experimentalvalidation. literature abstract metadata
- T2 Gentiopicroside Ameliorates Psoriasis-Like Dermatitis by Modulating Immune Homeostasis and Suppressing NF-κB Activation. literature abstract metadata
- T2 Metabolome and transcriptome analyses reveal metabolic differences and identify candidate regulatory factors among three habitat types of Gentiana scabra Bunge. literature abstract metadata