Japanese gentian
Gentiana scabra
Gentiana scabra is a traditional Chinese medicinal plant. It has been used in various practices, particularly within Traditional Chinese Medicine (TCM), for its purported health benefits. Scientific studies have shown that Gentiana scabra exhibits potential therapeutic effects, including modulation of immune responses and reduction of blood pressure. For instance, GPS treatment derived from this plant was found to alleviate psoriasis-like skin lesions by modulating immune homeostasis and suppressing NF-κB activation in mice. Additionally, it has been observed to lower blood pressure in rats with chronic stress-induced hypertension through the modulation of multiple signaling pathways. Gentiana scabra extract also showed varying efficacy against Eimeria tenella-induced coccidiosis in broilers, with a 2 g/kg dose achieving optimal results by improving gut health and modulating the microbiota-metabolome. To date, no major safety issues or drug interactions have been recorded for this plant, but further research is needed to fully understand its potential applications and mechanisms of action.
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 在野生灌木丛、野生草地和耕作农田中生长的龙胆草（Gentiana scabra）中，发现了代谢差异和基因表达变化。
- GPS治疗显著减轻了小鼠类似牛皮癣的皮肤病变，通过调节免疫稳态和抑制NF-κB激活。
- 研究发现，龙胆泻肝丸可能通过多种信号途径降低慢性应激性高血压大鼠的血压。
- 甘草蔓荆子提取物在肉鸡因艾美耳球虫（Eimeria tenella）引起的球虫病中表现出不同的疗效，最佳效果为每千克体重2克。
Frequently asked questions
What is Japanese gentian?
Japanese gentian (Gentiana scabra) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Japanese gentian?
4 sourced findings are recorded for Japanese gentian; the strongest carries evidence grade D. For example: 在野生灌木丛、野生草地和耕作农田中生长的龙胆草（Gentiana scabra）中，发现了代谢差异和基因表达变化。
How strong is the evidence for Japanese gentian?
The strongest finding for Japanese gentian carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Japanese gentian safe? What are the side effects?
No major safety issues are recorded for Japanese gentian in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Japanese gentian interact with medications?
No drug interactions are recorded for Japanese gentian in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Japanese gentian?
Japanese gentian is also known as: Горечавка шероховатая, Gentiane japonaise.
Is Japanese gentian a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Gentiana scabra mitigates Eimeria tenella-induced Coccidiosis by regulating the gut microbiota-metabolome and strengthening the intestinal barrier. literature abstract metadata
- T2 The mechanism of Longdan Xiegan pills in chronic stress-induced hypertension:a study based on network pharmacology and experimentalvalidation. literature abstract metadata
- T2 Gentiopicroside Ameliorates Psoriasis-Like Dermatitis by Modulating Immune Homeostasis and Suppressing NF-κB Activation. literature abstract metadata
- T2 Metabolome and transcriptome analyses reveal metabolic differences and identify candidate regulatory factors among three habitat types of Gentiana scabra Bunge. literature abstract metadata