Bigroot Geranium
Geranium macrorrhizum
Geranium macrorrhizum is a plant traditionally used in herbal medicine but lacks specific documented traditional uses. Scientific evidence suggests that it may have potential health benefits, particularly for mitigating gentamicin-induced nephrotoxicity by modulating oxidative stress and enhancing antioxidant enzymes in mice, based on one study comparing its phenolic diversity to Pelargonium radula. Additionally, some methanolic extracts from Geranium species, including G. macrorrhizum, showed selective cytotoxic activity against cancer cell lines, with the strongest activity observed in underground parts of G. sanguineum. Essential oils from cultivated Geranium macrorrhizum demonstrated strong activity against Trichomonas gallinae and Leishmania infantum, with germacrone identified as a key bioactive constituent. No major safety issues or recorded drug interactions have been noted for this plant.
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 某些甲醇提取物从紫锥菊属植物中显示出对癌细胞系的选择性细胞毒性，其中G. sanguineum地下部分的活性最强。
- The study found that Geranium macrorrhizum oil showed potential for mitigating gentamicin-induced oxidative stress and renal damage in mice, though no direct treatment claims are made.
- 大根菊显示了比仁慈薄荷更高的酚类多样性和丰富度。
- 来自Geranium macrorrhizum的精油对Trichomonas gallinae和Leishmania infantum显示出强大的活性，其中germacrone是关键生物活性成分。
Frequently asked questions
What is Bigroot Geranium?
Bigroot Geranium (Geranium macrorrhizum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Bigroot Geranium?
4 sourced findings are recorded for Bigroot Geranium; the strongest carries evidence grade D. For example: 某些甲醇提取物从紫锥菊属植物中显示出对癌细胞系的选择性细胞毒性，其中G. sanguineum地下部分的活性最强。
How strong is the evidence for Bigroot Geranium?
The strongest finding for Bigroot Geranium carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Bigroot Geranium safe? What are the side effects?
No major safety issues are recorded for Bigroot Geranium in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Bigroot Geranium interact with medications?
No drug interactions are recorded for Bigroot Geranium in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Bigroot Geranium?
Bigroot Geranium is also known as: Герань крупнокорневищная, Geranium a gros rhizome.
Is Bigroot Geranium a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Antioxidant Potential and Oxidative Stress Modulation of Geranium macrorrhizum L. Oil Extract in Gentamicin-Induced Nephrotoxicity. literature abstract metadata
- T2 Antiprotozoal Potential of Cultivated Geranium macrorrhizum Against Giardia duodenalis, Trichomonas gallinae and Leishmania infantum. literature abstract metadata
- T2 Comparative Phytochemical Analysis of the Aerial Parts of Pelargonium radula and Geranium macrorrhizum Cultivated in Bulgaria Using GC-MS and HPLC. literature abstract metadata
- T2 Phenolic Profiles and Cytotoxic Activities of Methanolic Extracts From Eight Geranium L. Species. literature abstract metadata