Geranium a gros rhizome
Geranium macrorrhizum · Bigroot Geranium
Geranium macrorrhizum is a plant traditionally used in herbal medicine but lacks specific documented traditional uses. Scientific evidence suggests that it may have potential health benefits, particularly for mitigating gentamicin-induced nephrotoxicity by modulating oxidative stress and enhancing antioxidant enzymes in mice, based on one study comparing its phenolic diversity to Pelargonium radula. Additionally, some methanolic extracts from Geranium species, including G. macrorrhizum, showed selective cytotoxic activity against cancer cell lines, with the strongest activity observed in underground parts of G. sanguineum. Essential oils from cultivated Geranium macrorrhizum demonstrated strong activity against Trichomonas gallinae and Leishmania infantum, with germacrone identified as a key bioactive constituent. No major safety issues or recorded drug interactions have been noted for this plant.
- Meilleure preuve
- D
- Précautions
- —
Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.
Ce que dit la science
- Certains extraits méthanoliques d'espèces de Geranium ont montré une toxicité sélective contre des lignées cellulaires cancéreuses, avec l'activité la plus forte chez les parties souterraines de G. sanguineum.
- The study found that Geranium macrorrhizum oil showed potential for mitigating gentamicin-induced oxidative stress and renal damage in mice, though no direct treatment claims are made.
- Le geranium macrorrhiza a montré une plus grande diversité et abondance phénolique par rapport à pelargonium radula.
- Les huiles essentielles de Geranium macrorrhizum ont montré une activité forte contre Trichomonas gallinae et Leishmania infantum, avec le germacrone étant un composant bioactif clé.
Frequently asked questions
What is Geranium a gros rhizome?
Geranium a gros rhizome (Geranium macrorrhizum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Geranium a gros rhizome?
4 sourced findings are recorded for Geranium a gros rhizome; the strongest carries evidence grade D. For example: Certains extraits méthanoliques d'espèces de Geranium ont montré une toxicité sélective contre des lignées cellulaires cancéreuses, avec l'activité la plus forte chez les parties souterraines de G. sanguineum.
How strong is the evidence for Geranium a gros rhizome?
The strongest finding for Geranium a gros rhizome carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Geranium a gros rhizome safe? What are the side effects?
No major safety issues are recorded for Geranium a gros rhizome in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Geranium a gros rhizome interact with medications?
No drug interactions are recorded for Geranium a gros rhizome in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Geranium a gros rhizome?
Geranium a gros rhizome is also known as: Bigroot Geranium, Герань крупнокорневищная.
Is Geranium a gros rhizome a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Antioxidant Potential and Oxidative Stress Modulation of Geranium macrorrhizum L. Oil Extract in Gentamicin-Induced Nephrotoxicity. literature abstract metadata
- T2 Antiprotozoal Potential of Cultivated Geranium macrorrhizum Against Giardia duodenalis, Trichomonas gallinae and Leishmania infantum. literature abstract metadata
- T2 Comparative Phytochemical Analysis of the Aerial Parts of Pelargonium radula and Geranium macrorrhizum Cultivated in Bulgaria Using GC-MS and HPLC. literature abstract metadata
- T2 Phenolic Profiles and Cytotoxic Activities of Methanolic Extracts From Eight Geranium L. Species. literature abstract metadata