Christmas-rose
Helleborus
Helleborus，一种多年生开花植物属，原产于欧洲、亚洲和北非，具有悠久的传统用途历史。虽然单个物种的具体传统用途记录不多，但黑根雪胆（Helleborus niger）在欧洲民间医学中曾被用于治疗各种疾病，包括作为泻药和利尿剂。科学证据有限，但表明可能有一些潜在的好处；一项研究显示，与对照组相比，皮下注射黑根雪胆12x可能改善了认知功能，但这需要进一步验证。另一项研究从西藏雪胆中分离出两种新的甾体皂苷，这些皂苷对测试的癌细胞系没有显著的细胞毒性，而第三项研究发现，来自胡椒雪胆根部提取物具有抗氧化作用，并在细菌和哺乳动物细胞中诱导了细胞毒性效应。目前的安全数据尚不明确，但未报告任何重大问题；同样，目前也没有记录到药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 研究发现，在根据17个性状评估的51种虎耳草属杂交品种中存在丰富的表型多样性。
- 研究发现，接受皮下注射Helleborus niger 12x的患者在迷你精神状态检查中的评分与对照组相比有统计学上的显著改善。
- 从Helleborus thibetanus中分离出两种新的类固醇皂苷，但在测试的癌细胞系中未显示显著的细胞毒性。
- 胡椒胡椒根提取物显示出抗氧化作用，并在细菌和哺乳动物细胞中诱导了细胞毒性效应。
- 在新西兰的 V. opulus 植物中发现了一种新的卡拉病毒，命名为“viburnum carlavirus 1”（VibCV1），与赫勒博鲁斯斑纹病毒密切相关，但可能代表一种新物种。
Frequently asked questions
What is Christmas-rose?
Christmas-rose (Helleborus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Christmas-rose?
5 sourced findings are recorded for Christmas-rose; the strongest carries evidence grade D. For example: 研究发现，在根据17个性状评估的51种虎耳草属杂交品种中存在丰富的表型多样性。
How strong is the evidence for Christmas-rose?
The strongest finding for Christmas-rose carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Christmas-rose safe? What are the side effects?
No major safety issues are recorded for Christmas-rose in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Christmas-rose interact with medications?
No drug interactions are recorded for Christmas-rose in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Christmas-rose?
Christmas-rose is also known as: морозник, hellébore.
Is Christmas-rose a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Two new steroidal saponins from the roots and rhizomes of Helleborus thibetanus. literature abstract metadata
- T2 Analysis of Phenotypic Diversity and Comprehensive Evaluation of 51 Helleborus L. Hybrid Individuals. literature abstract metadata
- T2 Identification and characterization of a novel carlavirus isolated from viburnum (Viburnum opulus) in Aotearoa New Zealand. literature abstract metadata
- T2 Subcutaneous application of Helleborus niger 12x in older patients with dementia-a retrospective cohort study. literature abstract metadata
- T2 Helleborus odorus subsp. cyclophyllus: An Unexploited Source of Antioxidant, Antimicrobial, and Cytotoxic Bioactivity. literature abstract metadata