Kopsia
Kopsia
Kopsia is a genus of plants traditionally not used in any known medicinal practices. Scientific studies have focused on its chemical composition, particularly the isolation and synthesis of various alkaloids from Kopsia species. Five monoterpenoid indole alkaloids were synthesized from the Kopsia genus using non-biomimetic strategies, with ten aspidofractinine-type alkaloids identified in Kopsia officinalis roots, showing potent cytotoxic activity against certain cancer cell lines. Four bisindole alkaloids isolated from Kopsia hainanensis demonstrated moderate inhibitory effects on lung cancer cells, though the potencies varied. No significant safety concerns or drug interactions have been recorded for this plant genus.
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 从Kopsia officinalis根中鉴定出10种aspidofractinine型生物碱，其中一种显示出对某些癌细胞系的潜在细胞毒性活性。
- The study achieved the divergent total synthesis of five monoterpenoid indole alkaloids from Kopsia using a non-biomimetic strategy.
- 科皮亚生物碱，包括科皮亚阿尔伯林B和科皮亚芬，对多种癌细胞系显示出了细胞毒性活性。
- 科皮莱库因A-D，来自科皮亚海南海森斯的双吲哚生物碱，在对抗肺癌细胞方面表现出细胞毒性活性。
Frequently asked questions
What is Kopsia?
Kopsia (Kopsia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Kopsia?
4 sourced findings are recorded for Kopsia; the strongest carries evidence grade D. For example: 从Kopsia officinalis根中鉴定出10种aspidofractinine型生物碱，其中一种显示出对某些癌细胞系的潜在细胞毒性活性。
How strong is the evidence for Kopsia?
The strongest finding for Kopsia carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Kopsia safe? What are the side effects?
No major safety issues are recorded for Kopsia in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Kopsia interact with medications?
No drug interactions are recorded for Kopsia in our sources. This does not rule them out — check with a pharmacist.
Is Kopsia a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Kopsileuconines A-D: Bisindole alkaloids with cytotoxic activity from Kopsia hainanensis. literature abstract metadata
- T2 Divergent Synthesis of Kopsia and Structurally Related Monoterpenoid Indole Alkaloids: A Non-biomimetic Strategy. literature abstract metadata
- T2 New aspidofractinine-type alkaloids with cytotoxic activity from the roots of Kopsia officinalis. literature abstract metadata
- T2 Unlocking the cytotoxic potential of Apocynaceae monoterpene indole and bis-indole alkaloids: a review. literature abstract metadata