FolkKB

Kopsia arborea

Kopsia arborea

科皮亚arborea是一种传统上未在任何已知医疗实践中使用的植物。科学研究已经从科皮亚arborea中鉴定出几种新的生物碱，这些生物碱对细胞周期依赖性蛋白激酶5和tau磷酸化显示出不同程度的抑制作用，尽管证据尚不充分，仍需进一步研究以确认这些发现。该植物还含有两种新的单萜吲哚生物碱，在体外评估了其细胞毒性，并在HT-29细胞中表现出生长抑制活性，在六种人类肺癌细胞系中表现出显著的细胞毒性活性。科皮亚arborea的安全性问题似乎并不严重，但尚未进行广泛的安全部研究。同样，目前没有关于该植物与药物之间潜在相互作用的信息。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 来自Kopsia arborea的三种新生物碱抑制cyclin依赖性激酶5和tau磷酸化，但效果在强度上有所不同。 D PMID
  • 从Kopsia arborea的种子中鉴定出了两种新的单萜吲哚生物碱，同时还发现了已知的生物碱，但没有报告出显著的健康影响。 D PMID
  • Three new alkaloids were isolated from Kopsia arborea, including one with a unique carbon-nitrogen skeleton and two incorporating a tetrahydrofuranone ring, showing in vitro growth inhibitory activity against HT-29 cells. D PMID
  • 从Kopsia arborea中分离出三种新的单萜吲哚生物碱，显示出对六种人类肺癌细胞系的显著细胞毒性活性。 D PMID

Frequently asked questions

What is Kopsia arborea?

Kopsia arborea (Kopsia arborea) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Kopsia arborea?

4 sourced findings are recorded for Kopsia arborea; the strongest carries evidence grade D. For example: 来自Kopsia arborea的三种新生物碱抑制cyclin依赖性激酶5和tau磷酸化，但效果在强度上有所不同。

How strong is the evidence for Kopsia arborea?

The strongest finding for Kopsia arborea carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Kopsia arborea safe? What are the side effects?

No major safety issues are recorded for Kopsia arborea in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Kopsia arborea interact with medications?

No drug interactions are recorded for Kopsia arborea in our sources. This does not rule them out — check with a pharmacist.

Is Kopsia arborea a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 A Cytotoxic Indole Characterized by Incorporation of a Unique Carbon-Nitrogen Skeleton and Two Pentacyclic Corynanthean Alkaloids Incorporating a Substituted Tetrahydrofuranone Ring from Kopsia arborea. literature abstract metadata
  2. T2 Cytotoxic monoterpenoid indole alkaloids from the aerial part of Kopsia arborea. literature abstract metadata
  3. T2 Two new monoterpenoid indole alkaloids from the kernels of Kopsia arborea. literature abstract metadata
  4. T2 Monoterpenoid indole alkaloid dimers from Kopsia arborea inhibit cyclin-dependent kinase 5 and tau phosphorylation. literature abstract metadata