Kopsia arborea
Kopsia arborea
Kopsia arborea is a plant traditionally used in limited or unrecorded practices. Scientific research has identified several new alkaloids from Kopsia arborea, including those with inhibitory activity against cyclin-dependent kinase 5 and tau phosphorylation, though the evidence for these effects is not strongly established. The isolated monoterpenoid indole alkaloids have shown significant cytotoxic activity against human lung cancer cell lines in vitro, but further research is needed to confirm their potential therapeutic value. No major safety concerns or drug interactions have been recorded, suggesting that Kopsia arborea may be generally safe for use; however, the lack of extensive clinical trials means that its full safety profile remains unclear.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Three new alkaloids from Kopsia arborea inhibit cyclin-dependent kinase 5 and tau phosphorylation, though effects vary in potency.
- Two new monoterpenoid indole alkaloids were identified from Kopsia arborea kernels along with known alkaloids, but no significant health effects are reported.
- Three new alkaloids were isolated from Kopsia arborea, including one with a unique carbon-nitrogen skeleton and two incorporating a tetrahydrofuranone ring, showing in vitro growth inhibitory activity against HT-29 cells.
- Three new monoterpenoid indole alkaloids were isolated from Kopsia arborea, showing significant cytotoxic activity against six human lung cancer cell lines.
Frequently asked questions
What is Kopsia arborea?
Kopsia arborea (Kopsia arborea) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Kopsia arborea?
4 sourced findings are recorded for Kopsia arborea; the strongest carries evidence grade D. For example: Three new alkaloids from Kopsia arborea inhibit cyclin-dependent kinase 5 and tau phosphorylation, though effects vary in potency.
How strong is the evidence for Kopsia arborea?
The strongest finding for Kopsia arborea carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Kopsia arborea safe? What are the side effects?
No major safety issues are recorded for Kopsia arborea in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Kopsia arborea interact with medications?
No drug interactions are recorded for Kopsia arborea in our sources. This does not rule them out — check with a pharmacist.
Is Kopsia arborea a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 A Cytotoxic Indole Characterized by Incorporation of a Unique Carbon-Nitrogen Skeleton and Two Pentacyclic Corynanthean Alkaloids Incorporating a Substituted Tetrahydrofuranone Ring from Kopsia arborea. literature abstract metadata
- T2 Cytotoxic monoterpenoid indole alkaloids from the aerial part of Kopsia arborea. literature abstract metadata
- T2 Two new monoterpenoid indole alkaloids from the kernels of Kopsia arborea. literature abstract metadata
- T2 Monoterpenoid indole alkaloid dimers from Kopsia arborea inhibit cyclin-dependent kinase 5 and tau phosphorylation. literature abstract metadata