Cape Hemp
Leonotis leonurus
Leonotis leonurus, also known as lion's ear, is a traditional plant native to southern Africa. Traditionally, its use has not been extensively documented in specific medicinal or ritual practices. Scientific studies have shown that leonurine, a compound found in Leonotis leonurus, modulates TRPA1 and TRPV4 channels, potentially reducing mechanical allodynia in a thalidomide-induced neuropathy model. Additionally, the smoke extract and isolated compounds from this plant demonstrated potential anticonvulsant and anxiolytic activity in zebrafish larvae, highlighting its possible neurological effects. The plant has been included among several psychoactive plants commonly used or abused in southern Africa, alongside other notable species such as Boophone disticha and Datura stramonium. No major safety issues have been recorded for Leonotis leonurus, nor are there any known drug interactions reported at this time.
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同,请查阅所引来源。
科学怎么说
- leonurine 调节TRPA1和TRPV4通道,减少由thalidomide诱导的神经病变模型中的机械性allodynia。
- 该研究更新了南部非洲药用和仪式植物的清单,自2002年以来新增了1239个新种类。
- 莱翁蒂斯·雷欧努拉斯的烟雾提取物和分离化合物在斑马鱼幼体中显示出潜在的抗惊厥和镇静活性。
- 研究发现,莱翁蒂斯·leonurus 在南部非洲常与其他精神活性植物一起被用于多种目的而被使用或滥用。
Frequently asked questions
What is Cape Hemp?
Cape Hemp (Leonotis leonurus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Cape Hemp?
4 sourced findings are recorded for Cape Hemp; the strongest carries evidence grade D. For example: leonurine 调节TRPA1和TRPV4通道,减少由thalidomide诱导的神经病变模型中的机械性allodynia。
How strong is the evidence for Cape Hemp?
The strongest finding for Cape Hemp carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Cape Hemp safe? What are the side effects?
No major safety issues are recorded for Cape Hemp in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Cape Hemp interact with medications?
No drug interactions are recorded for Cape Hemp in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Cape Hemp?
Cape Hemp is also known as: Леонотис пустырниковый.
Is Cape Hemp a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Chemical profiling, anticonvulsant and anxiolytic effects of the smoke constituents isolated from Leonotis leonurus (L.) R.Br. literature abstract metadata
- T2 An updated inventory of medicinal and ritual plants of southern Africa. literature abstract metadata
- T2 The use and potential abuse of psychoactive plants in southern Africa: an overview of evidence and future potential. literature abstract metadata
- T2 Anti-nociceptive action of leonurine through TRPA1 and TRPV4 channels modulation. literature abstract metadata