Purple Gromwell
Lithospermum erythrorhizon
紫草属植物Lithospermum erythrorhizon，又称紫草或中国龙胆，是一种传统草药，在东方医学中主要用于治疗各种皮肤状况和炎症。传统上，它被用于治疗多种皮肤疾病和炎症，尽管不同传统的具体用途有所不同。科学研究表明，L. erythrorhizon 中发现的主要活性成分紫草素通过多种机制表现出抗炎和抗癌作用；然而，由于潜在的毒性问题，临床应用受到限制。荟萃分析表明，紫草素可以显著减少实验性类风湿性关节炎模型中的足肿胀和关节炎评分。此外，在动物模型的特应性皮炎中，紫草治疗显示出减轻皮肤炎症严重程度和抓挠行为的有效性，尽管其对表皮屏障修复的影响较小。L. erythrorhizon 的安全性概况似乎是有利的，没有记录到主要问题；同样，目前还没有报告与该草药相关的药物相互作用。
- 最佳证据
- A
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 研究发现，经过基因编辑的LePPO1毛根，一种多酚氧化酶基因，显示shikonin含量降低而其他代谢物未受影响。
- 紫草素通过多种机制表现出抗炎和抗癌作用，但其临床应用受限于潜在毒性。
- 元分析表明，紫草素在实验性RA模型中显著减少了足垫水肿和关节炎评分。
- Zicao治疗显著降低了动物模型中特应性皮炎的严重程度和抓挠行为，但对表皮屏障恢复的作用有限。
Frequently asked questions
What is Purple Gromwell?
Purple Gromwell (Lithospermum erythrorhizon) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Purple Gromwell?
4 sourced findings are recorded for Purple Gromwell; the strongest carries evidence grade A. For example: 研究发现，经过基因编辑的LePPO1毛根，一种多酚氧化酶基因，显示shikonin含量降低而其他代谢物未受影响。
How strong is the evidence for Purple Gromwell?
The strongest finding for Purple Gromwell carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Purple Gromwell safe? What are the side effects?
No major safety issues are recorded for Purple Gromwell in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Purple Gromwell interact with medications?
No drug interactions are recorded for Purple Gromwell in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Purple Gromwell?
Purple Gromwell is also known as: vorobejnik krasnokornevoj.
Is Purple Gromwell a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 A meta-analysis of the traditional herb Zicao and its active components for atopic dermatitis. literature abstract metadata
- T2 Shikonin: Unraveling its Multi-Mechanistic Anticancer and Anti- Inflammatory Mechanisms. literature abstract metadata
- T2 Immunopharmacological effects of shikonin in experimental rheumatoid arthritis: a systematic review and meta-analysis of in vivo studies. literature abstract metadata
- T2 CRISPR/Cas9-mediated genome editing reveals the involvement of a polyphenol oxidase in the shikonin-specific biosynthesis in Lithospermum erythrorhizon. literature abstract metadata