Common Gromwell
Lithospermum officinale
Lithospermum officinale，又称中国苦胆或铅华根，源自东亚的传统医学实践。它传统上用于治疗烧伤和皮肤状况等多种用途，尽管与痤疮相关的具体用途尚未得到充分记录。科学研究表明，外用Lithospermum officinale提取物在减少炎症性及非炎症性痤疮病变方面表现出显著效果，并且对照组安慰剂的对比研究中未出现严重不良反应。该植物含有超过2%干重的黄酮类化合物，这可能有助于其潜在的有效性。此外，从这种植物中发现的紫草素通过多种机制抑制甲状腺癌细胞迁移和侵袭，而与其他抗癌药物之间没有报告交叉耐药性。尚未记录有关Lithospermum officinale的重大安全问题或药物相互作用。
- 最佳证据
- B
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 来自Lithospermum officinale的鞘闾素通过多种机制抑制甲状腺癌细胞迁移和侵袭，而不对其他抗癌剂产生交叉耐药性。
- 紫草 officinale 含有多种生物活性植物化学物质，具有潜在的药理作用。
- 与对照组相比，紫草属植物Lithospermum officinale组的炎症性和非炎症性痤疮病灶数量显著减少，且未出现严重不良事件。
- 该研究开发了一种方法来定量测定 Lithospermum officinale 叶片中的黄酮类化合物，发现其含量超过干重的 2%。
Frequently asked questions
What is Common Gromwell?
Common Gromwell (Lithospermum officinale) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Common Gromwell?
4 sourced findings are recorded for Common Gromwell; the strongest carries evidence grade B. For example: 来自Lithospermum officinale的鞘闾素通过多种机制抑制甲状腺癌细胞迁移和侵袭，而不对其他抗癌剂产生交叉耐药性。
How strong is the evidence for Common Gromwell?
The strongest finding for Common Gromwell carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Common Gromwell safe? What are the side effects?
No major safety issues are recorded for Common Gromwell in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Common Gromwell interact with medications?
No drug interactions are recorded for Common Gromwell in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Common Gromwell?
Common Gromwell is also known as: Воробейник лекарственный.
Is Common Gromwell a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Clinical efficacy of herbal extracts in treatment of mild to moderate acne vulgaris: an 8-week, double-blinded, randomized, controlled trial. literature abstract metadata
- T2 Research Progress of the Molecular Mechanism of Antithyroid Cancer Activity of Shikonin. literature abstract metadata
- T2 Development and Validation of a Method to Quantify Flavonoids in Leaves of Lithospermum officinale (Boraginaceae). literature abstract metadata
- T2 Exploring the Pharmacological Potential of Lithospermum officinale L.: A Review of Phytochemicals and Ethnomedicinal Uses. literature abstract metadata