Common Gromwell
Lithospermum officinale
Lithospermum officinale，常被称为中国甘草或 Lithospermum，是一种在东亚医学中使用的传统植物。虽然其具体应用尚未得到广泛记录，但已对其多种潜在健康益处进行研究。科学证据表明，该植物中的 shikonin 可能通过多种机制抑制甲状腺癌细胞的迁移和侵袭，并且不会出现与其他抗癌药物交叉耐药性。此外，局部使用 Lithospermum officinale 在减少炎症性和非炎症性痤疮病变数量方面显示出前景，且未报告严重不良事件。研究还量化了该植物叶片中的黄酮类化合物，其含量超过干重的 2 %。 关于 Lithospermum officinale 的安全记录没有发现主要问题；然而，由于研究有限，应密切监测其使用。目前尚无与此植物的药物相互作用记录，但需要进一步研究以充分了解其潜在影响和相互作用。
- 最佳证据
- B
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 来自Lithospermum officinale的鞘闾素通过多种机制抑制甲状腺癌细胞迁移和侵袭，而不对其他抗癌剂产生交叉耐药性。
- 紫草 officinale 含有多种生物活性植物化学物质，具有潜在的药理作用。
- 与对照组相比，紫草属植物Lithospermum officinale组的炎症性和非炎症性痤疮病灶数量显著减少，且未出现严重不良事件。
- 该研究开发了一种方法来定量测定 Lithospermum officinale 叶片中的黄酮类化合物，发现其含量超过干重的 2%。
Frequently asked questions
What is Common Gromwell?
Common Gromwell (Lithospermum officinale) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Common Gromwell?
4 sourced findings are recorded for Common Gromwell; the strongest carries evidence grade B. For example: 来自Lithospermum officinale的鞘闾素通过多种机制抑制甲状腺癌细胞迁移和侵袭，而不对其他抗癌剂产生交叉耐药性。
How strong is the evidence for Common Gromwell?
The strongest finding for Common Gromwell carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Common Gromwell safe? What are the side effects?
No major safety issues are recorded for Common Gromwell in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Common Gromwell interact with medications?
No drug interactions are recorded for Common Gromwell in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Common Gromwell?
Common Gromwell is also known as: Воробейник лекарственный.
Is Common Gromwell a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Clinical efficacy of herbal extracts in treatment of mild to moderate acne vulgaris: an 8-week, double-blinded, randomized, controlled trial. literature abstract metadata
- T2 Research Progress of the Molecular Mechanism of Antithyroid Cancer Activity of Shikonin. literature abstract metadata
- T2 Development and Validation of a Method to Quantify Flavonoids in Leaves of Lithospermum officinale (Boraginaceae). literature abstract metadata
- T2 Exploring the Pharmacological Potential of Lithospermum officinale L.: A Review of Phytochemicals and Ethnomedicinal Uses. literature abstract metadata