devil's tobacco

Lobelia tupa

洛贝利亚·图帕是一种传统上在南美洲民间医学中使用的植物,特别是由土著社区使用。尽管其具体用途尚未详细记录,但对其潜在药理作用进行了研究。科学研究表明,洛贝利亚·图帕含有对癌症细胞中的关键信号通路具有调节作用的植物成分,特别是在肺和结肠癌方面。此外,该植物中的一种生物碱——戊基塞丁因,作为烟碱型乙酰胆碱受体的部分激动剂起作用。在另一项研究中,洛贝利亚·图帕提取物在六天内对储藏谷物害虫的死亡率高达45%至80%,而洛贝兰定显示出适度活性。迄今为止,尚未记录该植物的重大安全问题或药物相互作用,但进一步的研究对于完全了解其潜在益处和风险是必要的。

速览
最佳证据
D
注意事项

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同,请查阅所引来源。

科学怎么说

  • 研究鉴定出来自11种传统药用植物(包括洛贝拉·图帕)的多种植物成分,这些成分可以调节肺癌和结肠癌细胞中的关键信号通路。 D PMID
  • 研究发现,CYC同源基因的复制和表达模式在不同科的Campanulaceae中有所不同,影响花的对称性。 D PMID
  • 从洛贝lia·图帕中提取的物质在6天内使谷斑皮蠹的死亡率从45%到80%。 D EPMC
  • pentylsedinine,来自Lobelia tupa的生物碱,作为尼古丁乙酰胆碱受体的部分激动剂。 D PMID

Frequently asked questions

What is devil's tobacco?

devil's tobacco (Lobelia tupa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about devil's tobacco?

4 sourced findings are recorded for devil's tobacco; the strongest carries evidence grade D. For example: 研究鉴定出来自11种传统药用植物(包括洛贝拉·图帕)的多种植物成分,这些成分可以调节肺癌和结肠癌细胞中的关键信号通路。

How strong is the evidence for devil's tobacco?

The strongest finding for devil's tobacco carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is devil's tobacco safe? What are the side effects?

No major safety issues are recorded for devil's tobacco in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does devil's tobacco interact with medications?

No drug interactions are recorded for devil's tobacco in our sources. This does not rule them out — check with a pharmacist.

Is devil's tobacco a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Assessment of insecticidal responses of extracts and compounds of Drimys winteri, Lobelia tupa, Viola portalesia and Vestia foetida against the granary weevil Sitophilus granarius literature abstract metadata
  2. T2 (-)-Pentylsedinine, a New Alkaloid from the Leaves of Lobelia tupa with Agonist Activity at Nicotinic Acetylcholine Receptor. literature abstract metadata
  3. T2 Duplication and expression patterns of CYCLOIDEA-like genes in Campanulaceae. literature abstract metadata
  4. T2 Interplay Between Traditional and Scientific Knowledge: Phytoconstituents and Their Roles in Lung and Colorectal Cancer Signaling Pathways. literature abstract metadata