devil's tobacco
Lobelia tupa
卷叶龙胆（Lobelia tupa）是一种属于龙胆科的植物。在某些传统医学中，它被用于治疗尼古丁成瘾。科学研究表明，其所含的生物碱戊基赛地宁（pentylsedinine）在烟碱型乙酰胆碱受体上起部分激动剂的作用，并且该植物的提取物对谷物象鼻虫（Sitophilus granarius）具有杀虫作用。一些研究表明，某些植物化学成分可能调节特定癌细胞系的信号通路，但需要进一步研究以明确这些作用。现有数据表明，该植物没有出现重大安全问题或明显的药物相互作用。
- 传统用于
- 尼古丁成瘾的治疗
- 传统体系
- 西方植物疗法
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
传统用途
- 尼古丁成瘾的治疗
科学怎么说
- 研究鉴定出来自11种传统药用植物（包括洛贝拉·图帕）的多种植物成分，这些成分可以调节肺癌和结肠癌细胞中的关键信号通路。
- 研究发现，CYC同源基因的复制和表达模式在不同科的Campanulaceae中有所不同，影响花的对称性。
- 从洛贝lia·图帕中提取的物质在6天内使谷斑皮蠹的死亡率从45%到80%。
- pentylsedinine，来自Lobelia tupa的生物碱，作为尼古丁乙酰胆碱受体的部分激动剂。
Frequently asked questions
What is devil's tobacco?
devil's tobacco (Lobelia tupa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What is devil's tobacco traditionally used for?
Traditional sources record devil's tobacco for: 尼古丁成瘾的治疗. This reflects traditional use, not a proven medical treatment.
Which traditions use devil's tobacco?
devil's tobacco appears in these traditions in our sources: Western phytotherapy.
What does the scientific evidence say about devil's tobacco?
4 sourced findings are recorded for devil's tobacco; the strongest carries evidence grade D. For example: 研究鉴定出来自11种传统药用植物（包括洛贝拉·图帕）的多种植物成分，这些成分可以调节肺癌和结肠癌细胞中的关键信号通路。
How strong is the evidence for devil's tobacco?
The strongest finding for devil's tobacco carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is devil's tobacco safe? What are the side effects?
No major safety issues are recorded for devil's tobacco in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does devil's tobacco interact with medications?
No drug interactions are recorded for devil's tobacco in our sources. This does not rule them out — check with a pharmacist.
Is devil's tobacco a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Assessment of insecticidal responses of extracts and compounds of Drimys winteri, Lobelia tupa, Viola portalesia and Vestia foetida against the granary weevil Sitophilus granarius literature abstract metadata
- T2 (-)-Pentylsedinine, a New Alkaloid from the Leaves of Lobelia tupa with Agonist Activity at Nicotinic Acetylcholine Receptor. literature abstract metadata
- T2 Duplication and expression patterns of CYCLOIDEA-like genes in Campanulaceae. literature abstract metadata
- T2 Interplay Between Traditional and Scientific Knowledge: Phytoconstituents and Their Roles in Lung and Colorectal Cancer Signaling Pathways. literature abstract metadata
- T3 Lobelia tupa CC BY-SA 4.0